COMMENTARY: Review: Pharmacotherapy improves cognitive symptoms in dementia

Hirsch, Calvin
January 2005
ACP Journal Club;Jan/Feb2005, Vol. 142 Issue 1, p14
Academic Journal
The article reports that pharmacotherapy improves cognitive symptoms in dementia. Pharmacotherapy of dementia involves treatment aimed both at the underlying disease and associated behavioral problems that occur during the course of the dementia. Meta-analysis of the results from pooled trials suggests that • . donepezil, rivastigmine and galantamine have similar, small effect sizes for short-term cognitive improvement in Alzheimer disease. The concern that risperidone and olanzapine increase the risk for stroke has not been supported by a retrospective population-based cohort study of patients prescribed these medications.


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