COMMENTARY: Review: Clonidine is more effective than placebo for long-term smoking cessation but has side effects
- FDA's postmarketing review of varenicline and bupropion. // Reactions Weekly;1/24/2009, Issue 1236, p3
The article reports on the postmarketing review of Adverse Event Reporting System reports by the U.S. Food and Drug Administration (FDA) which identified cases of suicidal ideation and behaviours after taking varenicline and bupropion for smoking cessation. 41 percent of varenicline recipients...
- Preexposure to nicotine alters the subsequent locomotor stimulant effects of bupropion in rats. Wilkinson, Jamie; Palmatier, Matthew; Bevins, Rick // Nicotine & Tobacco Research;Feb2006, Vol. 8 Issue 1, p141
Little is known about the interaction between nicotine and bupropion (Zyban), but many studies suggest they have neurological and behavioral similarities. One feature of drugs with common profiles is the ability to cross-sensitize possibly through neurological changes in the reward pathway....
- Bupropion (Zyban, Wellbutrin SR): reports of deaths, seizures, serum sickness. Wooltorton, Eric // CMAJ: Canadian Medical Association Journal;1/8/2002, Vol. 166 Issue 1, p68
Focuses on suspected adverse drug reactions for bupropion, including reports of a number of deaths, seizures or convulsions, and serum-sickness-like reactions. How the drug appears to block noradrenergic reuptake and dopaminergic reuptake in the brain, and is used as an antidepressant and...
- Nicotine conjugate vaccines: A novel approach in smoking cessation. Kitchens, Caroline M.; Foster, Stephan L. // Journal of the American Pharmacists Association: JAPhA;Jan/Feb2012, Vol. 52 Issue 1, p116
The article discusses pharmacologic therapeutic options for smoking cessation in the U.S. These options are direct nicotine replacement therapy (NRT), anti-depressant medications and a nicotine receptor partial agonist. Dosage forms of NRT include chewing gums, lozenges, patches, nasal sprays...
- Antidepressants and Smoking Cessation. Kripke, Clarissa // American Family Physician;1/1/2005, Vol. 71 Issue 1, p67
Focuses on antidepressants that help patients stop smoking. Factors that increase the rates of abstinence from smoking; Practices approved by the U.S. Food and Drug Administration for use in smoking cessation; Antidepressants that improve rates of smoking cessation.
- Chantix and neuropsychiatric side effects. Elliott, William T. // Primary Care Reports;Dec2011 Pharmacology Watch, p2
The article presents the findings of two epidemiologic studies sponsored by the U.S. Food and Drug Administration (FDA) in 2011 which showed no difference in the risk of neuropsychiatric hospitalization between smoking cessation drug varenicline (Chantix) and nicotine replacement therapy.
- Antismoking drug comes under scrutiny after deaths. Dobson, Roger // BMJ: British Medical Journal (International Edition);02/24/2001, Vol. 322 Issue 7284, p452
Addresses complaints filed against the manufacturers of the antismoking drug amfebutamone (Zyban), following the deaths of 18 people who are suspected to have had adverse reactions to the drug. How the Medicines Control Agency said that the contribution of the drug to the deaths is unknown;...
- VARENICLINE. // Complete Guide to Prescription & Nonprescription Drugs 2012;2012, p830
The article presents information on varenicline, an antismoking agent, including its dosage, usage, adverse reactions, side effects, precautions when administering, and possible interaction with other drugs.
- Bupropion. // Reactions Weekly;1/24/2009, Issue 1236, p11
The article describes the case of a 34-year-old man who acquired rhabdomyolysis. The patient developed the said condition while undergoing treatment with bupropion as part of his smoking cessation therapy. He was asked to stop bupropion therapy and continued to use transdermal nicotine patch...