COMMENTARY: Esomeprazole was not better than omeprazole for resolving heartburn in endoscopy-negative reflux disease
- Selection of Patients for Successful Maintenance Treatment of Esophagitis With Low-Dose Omeprazole: Use of 24-Hour Gastric pH Monitoring. Ladas, Spiros D.; Tassios, Pericles S.; Raptis, Sotirios A. // American Journal of Gastroenterology;Feb2000, Vol. 95 Issue 2, p374
OBJECTIVE: Treating patients with erosive esophagitis and maintaining remission in a cost-effective fashion is a desirable goal in clinical practice. There are no established criteria to identify patients with healed esophagitis who will subsequently remain in remission with low-dose omeprazole...
- Heartburn. // American Family Physician;11/15/2003, Vol. 68 Issue 10, p2033
Provides information on heartburn. Definition; Causes; Tips on stopping heartburn.
- The Effect of Raw Onions on Acid Reflux and Reflux Symptoms. Allen, Melvin L.; Mellow, Mark H.; Robinson, Malcolm G.; Orr, William C. // American Journal of Gastroenterology;Apr1990, Vol. 85 Issue 4, p377
Patients with gastroesophageal reflux often describe heartburn after "spicy meals." One ingredient common to most such meals is onion. We investigated the effects of onion on acid reflux and reflux symptoms in 16 normal subjects and 16 heartburn subjects. Subjects were studied with an esophageal...
- The Relationship Between the Prevalence of Nighttime Gastroesophageal Reflux Disease and Disease Severity. Dean, Bonnie B.; Aguilar, Daniel; Johnson, Lawrence F.; Fass, Ronnie; Orr, William C.; McGuigan, James E.; Calimlim, Brian; Ning Yan; Morgenstern, Diana; Dubois, Robert W. // Digestive Diseases & Sciences;Apr2010, Vol. 55 Issue 4, p952
Nighttime gastrointestinal reflux disease (GERD) prevalence and severity estimates vary substantially across studies. We assessed nighttime GERD (NTG) prevalence and symptom frequency and severity through a web survey of US adults, using the GERD Symptom and Medication Questionnaire (GERD-SMQ),...
- Gastroesophageal reflux disease. Gianakos, Dean; Friedman, Lawrence S. // Patient Care;Jul2004, Vol. 38 Issue 7, p14
Presents a case study of a 28-year-old man diagnosed with gastroesophageal reflux disease (GERD). Medical history of the patient; Symptoms of GERD; Complications of GERD; Recommended treatment.
- Esophageal Mucosal Sensitivity: Possible Links with Clinical Presentations in Patients with Erosive Esophagitis and Laryngopharyngeal Reflux. Murat Korkmaz; Erkan Tarhan; Hakan Unal; Haldun Selcuk; Ugur Yilmaz; Levent Ozluoglu // Digestive Diseases & Sciences;Feb2007, Vol. 52 Issue 2, p451
Abstract??The goal of this study was to assess whether mucosal sensitivity is related to different combinations of symptoms and lesions in laryngopharyngeal reflux (LPR) and erosive esophagitis and to determine whether reflux pattern is important in the development of the symptoms and lesions of...
- Efficacy and Safety of Esomeprazole Compared With Omeprazole in GERD Patients With Erosive Esophagitis: A Randomized Controlled Trial. Richter, Joel E.; Kahrilas, Peter J.; Johanson, John; Maton, Paul; Breiter, Jeffrey R.; Hwang, Clara; Marino, Victoria; Hamelin, Bernard; Levine, Jeffrey G. // American Journal of Gastroenterology;Mar2001, Vol. 96 Issue 3, p656
OBJECTIVE: In patients with gastroesophageal reflux disease (GERD), esomeprazole. the S-isomer of omeprazole, has demonstrated pharmacological and clinical benefits beyond those seen with the racemic parent compound. This study was designed lo further evaluate the efficacy and...
- Assessing Symptoms in Gastroesophageal Reflux Disease: How Well Do Clinicians' Assessments Agree with Those of Their Patients? McColl, Elaine; Junghard, Ola; Wiklund, Ingela; Revicki, Dennis A. // American Journal of Gastroenterology;Jan2005, Vol. 100 Issue 1, p11
OBJECTIVES: This study aimed to determine the extent of agreement between clinicians and patients regarding assessments of reflux symptom severity in patients with gastroesophageal reflux disease.METHODS: Data were analyzed from four randomized clinical trials involving 2,674 patients treated...
- Reflux Esophagitis: Healed! Now What? Romero, Yvonne; Egan, Laurence J.; Muray, Joseph A. // American Journal of Gastroenterology;Feb2000, Vol. 95 Issue 2, p337
Offers observation on reflux esophagitis. Number of Americans who experience heartburn annually; Information on proton pump inhibitor; Primary inactivation pathway for omeprazole.