COMMENTARY: An early invasive strategy reduced death or MI better than a conservative strategy in unstable angina and non-STEMI at advanced age

Bates, Eric R
January 2005
ACP Journal Club;Jan/Feb2005, Vol. 142 Issue 1, p3
Academic Journal
The article focuses on the study that the TACTICS-TIMI 18 trial that randomized patients with non-ST-elevation acute coronary syndromes to an early invasive or an early conservative management strategy. Older patients had a higher risk for death or myocardial infarction at 6 months and these risks were substantially lowered with the invasive strategy. Risk for bleeding may be the most common reason for nor pursuing an invasive strategy in the elderly. This study showed higher rates of major bleeding and blood transfusion but not stroke in older patients.


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