TITLE

COMMENTARY: Review: Hormone replacement therapy may reduce the risk for death in younger but not older postmenopausal women

AUTHOR(S)
Furberg, Curt D.; Psaty, Bruce M.
PUB. DATE
January 2005
SOURCE
ACP Journal Club;Jan/Feb2005, Vol. 142 Issue 1, p1
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article reports that hormone replacement therapy (HRT) may reduce the risk for death in younger but not older postmenopausal women. A benefit for a specific cause of death ought to be accompanied by a benefit, or at least a trend, for cause-specific morbidity. The literature offers no such support. The most likely explanation for this difference by age is a chance subgroup finding in a meta-analysis with low power. The meta-analysis has not provided any plausible evidence that should influence the current guidelines for use of HRT.
ACCESSION #
15851758

 

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