The case for thrombolysis in acute major pulmonary embolism: hemodynamic benefits and beyond

Konstantinides, Stavros
November 2002
Intensive Care Medicine;Nov2002, Vol. 28 Issue 11, p1547
Academic Journal
Studies the use of thrombolytic agents in acute pulmonary embolism. Assessment on the hemodynamic benefits of thrombolysis; Association of bleeding risk with thrombolytic treatment; Identification of high-risk patients with a favorable risk-to-benefit ratio.


Related Articles

  • The presence of shock defines the threshold to initiate thrombolytic therapy in patients with pulmonary embolism. Wood, Kenneth E. // Intensive Care Medicine;Nov2002, Vol. 28 Issue 11, p1537 

    Evaluates the effects of hypoperfusion on the increase of mortality. Analysis of the outcomes in pulmonary embolism; Assessment on the result of the combination of embolus size and cardiopulmonary status; Effects of the potential mortality benefits on the hemorrhagic risks.

  • Thrombolysis Not Helpful for Unselected Patients with PE. Ebell, Mark // American Family Physician;1/15/2005, Vol. 71 Issue 2, p352 

    Discusses research being done on the use of thrombolytic therapy for patients with pulmonary embolism (PE). Reference to a study by S. Wan et al published in the August 10, 2004 issue of "Circulation"; Reduction in the likelihood of PE or death in patients with major hemodynamically unstable...

  • COMMENTARY: Persistent right ventricular dysfunction increased risk for recurrent venous thromboembolism after acute pulmonary embolism. Douketis, James; Kaatz, Scott // ACP Journal Club;Mar/Apr2007, Vol. 146 Issue 2, p46 

    The article presents the authors' views about a study which states that persistent right ventricular dysfunction (RVD) increased risk for recurrent venous thromboembolism (VTE) after acute pulmonary embolism (PE). Although the findings of the study has been associated with increased short-term...

  • THROMBOLYSIS AS AN ALTERNATIVE TO PULMONARY EMBOLECTOMY. Porter, John M. // Vascular Surgery;Nov/Dec1977, Vol. 11 Issue 6, p373 

    Discusses the potential application of thrombolysis as an alternative to pulmonary embolectomy. Incidence and acute survival statistics of pulmonary embolism; Role of heparin in the treatment of pulmonary embolism; Evaluation of streptokinase and urokinase as thrombolytic agents.

  • Is Thrombolytic Therapy Effective for Pulmonary Embolism? Almoosa, Khalid // American Family Physician;3/15/2002, Vol. 65 Issue 6, p1097 

    Pulmonary embolism is a disorder that is associated with significant morbidity and mortality. Right-sided heart failure and recurrent pulmonary embolism are the main causes of death associated with pulmonary embolism in the first two weeks after the embolic event. Thrombolysis is a potentially...

  • A Case of a Serpentine-like Right Atrial Thrombus Causing Pulmonary Embolism. Aksakal, Enbiya; Emet, Mücahit; Değirmenci, Hüsnü; Uzkeser, Mustafa // Journal of Academic Emergency Medicine Case Reports / Akademik A;2012, Vol. 3 Issue 4, p134 

    Right atrial thrombi are rare but cause mortality in approximately 30-40% of cases. Echocardiography is important for determining the causes of the cardiac origin of pulmonary embolism, and, simultaneously, mobile thrombi can be rarely visualized in the right atrium and pulmonary artery....

  • Salvage intraosseous thrombolysis and extracorporeal membrane oxygenation for massive pulmonary embolism. Northey, Luke Cameron; Shiraev, Timothy; Omari, Abdullah // Journal of Emergencies, Trauma & Shock;Jan-Mar2015, Vol. 8 Issue 1, p55 

    Intraosseous access is an alternative route of pharmacotherapy during cardiopulmonary resuscitation. Extracorporeal membrane oxygenation (ECMO) provides cardiac and respiratory support when conventional therapies fail. This case reports the use of intraosseous thrombolysis and ECMO in a patient...

  • Long-term benefit of thrombolytic therapy in patients with pulmonary embolism. Sharma, G.V.R.K.; Folland, E.D.; McIntyre, K.M.; Sasahara, A.A. // Vascular Medicine;2000, Vol. 5 Issue 2, p91 

    A total of 23 of the 40 patients who had angiographically proven pulmonary embolism and who had initially been randomized to an IV infusion of heparin ( n= 11) or a thrombolytic agent (urokinase or streptokinase, n = 12) were restudied after a mean follow-up of 7.4 years to measure the...

  • Thrombolysis and pulmonary embolism. Rowbury, Gemma // British Journal of Cardiac Nursing;Feb2013, Vol. 8 Issue 2, p80 

    Acute pulmonary embolism is a condition that is associated with serious morbidity and mortality. Thrombolysis is a therapeutic option advocated by national guidelines for patients with haemodynamic compromise. However, this treatment is the subject of debate and there are a number of...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics