Genetic hemochromatosis is a rare disease entity among French Basques: a center-based study from the General Hospital of Basque Country

Bauduer, F.; Scribans, C.; Renoux, M.; Borot, N.
August 2001
Annals of Hematology;Aug2001, Vol. 80 Issue 8, p472
Academic Journal
A center-based study from the general hospital of Basque country has been performed to evaluate the importance of genetic hemochromatosis among French Basques. A sample of 37 patients from 34 families fulfilling the diagnosis criteria of hemochromatosis was obtained. Only four of them were of Basque origin: two homozygotes for C282Y, one homozygote for H63D, and one heterozygote for C282Y. These results suggest a significant lower prevalence of genetic hemochromatosis in Basques than in people from other French regions (P=0.001). They underline further the biological specificity of this population.


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