Maternal group B streptococcal (GBS) genital tract colonization at term in women who have asymptomatic GBS bacteriuria

McKenna, David S.; Matson, Scott; Northern, Ike
December 2003
Infectious Diseases in Obstetrics & Gynecology;2003, Vol. 11 Issue 4, p203
Academic Journal
Objective: To determine the rate of positive group B streptococcus (CBS) cultures at 35-37 weeks gestation in women who have first trimester asymptomatic CBS bacteriuria. Methods: Pregnant women with asymptomatic first trimester CBS bacteriuria had genital cultures for CBS performed at 35-37 weeks gestational age. Serotyping was performed by the standard Lancefield capillary precipitin method. Results: Fifty-three women with positive urine cultures had genital cultures performed at 35-37 weeks. Sixteen of the 53 (30.2%; 95% confidence interval: 18.4-44.3%) third trimester vaginal cultures were positive for CBS. Five of eight (63%) of the women with typable urine serotypes had the same typable serotype in the third trimester genital culture. Conclusion: Genital tract cultures at 35-37 weeks for CBS correlate poorly with first trimester asymptomatic CBS bacteriuria. Recommendations for CBS prophylaxis in labor in women who have first trimester asymptomatic CBS bacteriuria should be investigated further and reconsidered.


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