Review: Of the various D-dimer assays, negative ELISA results are most useful for excluding a diagnosis of deep venous thrombosis or pulmonary emnbolism

November 2004
ACP Journal Club;Nov/Dec2004, Vol. 141 Issue 3, p77
Academic Journal
The article addresses the question as to what are the test characteristics of various D-dimer assays for diagnosis of deep venous thrombosis (DVT) or pulmonary embolism (PE). The article found out by way of a study conducted in this regard that for diagnosis of DVT, the ELISA and quantitative rapid ELISA are more sensitive than latex and whole-blood agglutination assays; ELISAs have negative LRs of 0.10 to 0.25. For diagnosis of pulmonary embolism, the ELISA and quantitative rapid ELISA are more sensitive than semiquantitative latex and whole-blood agglutination assays.


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