COMMENTARY: Adults who require inhaled corticosteroids benefits from a moderate starting dose

Thien, Frank
November 2004
ACP Journal Club;Nov/Dec2004, Vol. 141 Issue 3, p72
Academic Journal
iThe article presents a commentary on the study, which concluded that adults who require inhaled corticosteroids benefits from a moderate starting dose. Airway inflammation is the key pathologic feature of asthma, and ICSs remain the most effective anti-inflammatory medication and the cornerstone of asthma pharmacotherapy. However, some other features of asthma, such as airway smooth muscle dysfunction (manifesting as AHR), respond more slowly, and airway remodeling does not seem to respond to ICS at all.


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