TITLE

Review: Adults who require inhaled corticosteroids benefits from a moderate starting dose

PUB. DATE
November 2004
SOURCE
ACP Journal Club;Nov/Dec2004, Vol. 141 Issue 3, p72
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article addresses the question as to what is the optimum starting dose in patients with asthma not treated by inhaled corticosteroids (ICSs). The article adds that In patients with asthma who require inhaled corticosteroids, an initial high dose improves FEV but does not differ from moderate doses for other asthma outcomes. An initial moderate dose improves peak expiratory flow and reduces night waking more than a low dose. For this study, Randomized controlled trials (RCTs) comparing 2 different doses (including step-down therapy) of the same ICS for 4 weeks in patients with oral-steroid-independent asthma were chosen.
ACCESSION #
15303594

 

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