COMMENTARY: Adding aspirin to clopidogrel increased bleeding without reducing recurrent ischemic vascular events in high-risk patients

Hankey, Graeme J.
November 2004
ACP Journal Club;Nov/Dec2004, Vol. 141 Issue 3, p68
Academic Journal
The article presents a commentary on the study, which concluded that adding aspirin to clopidogrel increased bleeding without reducing recurrent ischemic vascular events in high-risk patients. The results of the MATCH trial are consistent with the known effects of aspirin in patients with TIA or ischemic stroke (1) and with the effects of the combination of aspirin and clopidogrel in acute coronary syndromes [2]. The MATCH trial compared aspirin plus clopidogrel with clopidogrel alone, rather than with aspirin alone.


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