Performance of given suspected blood indicator

Liangpunsakul, Suthat; Mays, Lori; Rex, Douglas K.
December 2003
American Journal of Gastroenterology;Dec2003, Vol. 98 Issue 12, p2676
Academic Journal
OBJECTIVES: Given Imaging (Yoqneam, Israel) has developed a suspected blood indicator (SBI) function for its wireless capsule endoscopy (WCE) software. The SBI detects blood and marks appropriate images for interrogation. The sensitivity and accuracy of SBI and its role in examining WCE studies is unknown. Our aim was to evaluate the accuracy of this new software in detecting small bowel lesions. METHODS: WCE reports of all patients referred for WCE in October and November, 2002, were reviewed. The images from each patient were reviewed by experienced gastroenterologists at 15 frames/s. The findings detected by gastroenterologists were compared to those recognized by SBI. Arteriovenous malformations (AVMs), ulcers, erosions, and sites of active bleeding were considered significant lesions. RESULTS: A total of 24 patients (16 women and eight men, mean age 59 yr) were studied during this period. The indications for the study were iron deficiency anemia in 18 patients and abdominal pain in six patients. A total of 109 lesions were identified by gastroenterologists (47 AVMs, 18 active bleeding ulcers, 18 ulcers without bleeding, and 26 erosions). Active bleeding seen by gastroenterologists was secondary to AVMs (five cases), jejunal ulcers (11 cases, all in the same patient), and gastric ulcers (two cases). A total of 31 potential areas of blood were identified by SBI. When compared to those findings recognized by gastroenterologists, 28 lesions were correctly identified (six AVMs, 13 active bleeding ulcers, (three AVMs and 10 jejunal ulcers), seven nonbleeding ulcers, and two nonbleeding erosions. The overall sensitivity, positive predictive value, and accuracy of SBI to detect significant small bowel lesions were 25.7%, 90%, and 34.8%, respectively. If only actively bleeding lesions in the small bowel were considered, SBI had sensitivity, positive predictive value, and accuracy of 81.2%, 81.3%, and 83.3%, respectively. CONCLUSIONS: SBI has good sensitivity and positive predictive value for actively bleeding lesions in the small bowel. Complete review of the study by the physician is still needed. SBI should be considered as a complementary and rapid screening tool for gastroenterologists to identify actively bleeding lesions.


Related Articles

  • Interpreting haematology test results. Ryan, Kate // Pulse;3/10/2003, Vol. 63 Issue 10, p56 

    Presents a guide to interpreting the results of some common hematology test results. Full blood count; Anemia; Iron deficiency; Macrocytosis; Vitamin B12 deficiency; Anemia of chronic disease; Polycythemia; Platelet abnormalities; Blood sedimentation; Hemoglobin electrophoresis; Parasitic...

  • Do those with positive faecal occult blood tests need upper gastrointestinal investigations if no colorectal cancer cause is found? Robisnon, M.H. // Gut;Oct2002, Vol. 51 Issue 4, p466 

    Examines the need for upper gastrointestinal investigations by those patients with positive faecal occult blood tests if no colorectal cancer is found. Investigation of iron deficiency anemia through colonoscopy and gastroscopy; Diagnosis of upper gastrointestinal cancers within two years of...

  • Pancreatic Metaplasia of the Gastric Mucosa in Pediatric Patients. Integlia, M. J.; Krishnamurthy, S.; Berhane, R.; Grand, R. J.; Dayal, Y. // American Journal of Gastroenterology;Sep1997, Vol. 92 Issue 9, p1553 

    Antropyloric and intestinal-type metaplasia of gastric columnar epithelial cells occurs commonly in the setting of atrophic gastritis in both adults and pediatric patients. Pancreatic metaplasia of gastric mucosa, although less common, has been reported in a variety of clinical conditions in...

  • Feasibility of screening toddlers for iron deficiency anaemia in general practice. James, John A.; Laing, Gabrielle J. // BMJ: British Medical Journal (International Edition);07/12/97, Vol. 315 Issue 7100, p102 

    Presents results of a study regarding the feasibility of screening toddlers for iron deficiency anaemia in general practice in Great Britain. Method of data collection; Percent of parents who refused screening; Percent of patients who declined screening.

  • Not all transfused patients really need blood. Cerrato, Paul L. // RN;Aug93, Vol. 56 Issue 8, p16 

    Reports on the unnecessary blood transfusions given to iron-deficient patients according to a study by S. Saxena and A.P. Rabinowitz. Risk for blood borne infections; Treatment of oral or parenteral iron therapy.

  • The study of relationship between helicobacter pylori and Iron Deficiency Anemia in patient who referred to hematological clinic in Educational Emam Khomeini hospital. Rabieipoor, Masome; Maleki, Davood; Kazemzade, Jafar; Rabieipoor, Soheila; Behrozian, Ramin; Agdashi, Mir Amir // Annals of Biological Research;2011, Vol. 2 Issue 5, p449 

    Iron deficiency is estimated to be the most common nutritional deficiency in both developed and underdeveloped nations. Despite a thorough clinical and endoscopic evaluation, large case series have shown that more than one-third of patients do not have a lesion to account for their iron...

  • A Prospective, Multidisciplinary Evaluation of Premenopausal Women With Iron-Deficiency Anemia. Kepczyk, Thomas; Cremins, James E.; Long, Brian D.; Bachinski, Matthew B. Z.; Smith, L. Ramona; McNally, Peter R. // American Journal of Gastroenterology;Jan1999, Vol. 94 Issue 1, p109 

    Objective: The cause of iron deficiency anemia (IDA) in premenopausal women is often presumed to be menstrual blood loss. The purpose of this study was to determine the diagnostic value of a comprehensive gynecological and gastrointestinal evaluation in premenopausal women with IDA. Methods:...

  • Evaluation of Anemia in Children. JANUS, JENNIFER; MOERSCHEL, SARAH K. // American Family Physician;6/15/2010, Vol. 81 Issue 12, p1462 

    Anemia is defined as a hemoglobin level of less than the 5th percentile for age. Causes vary by age. Most children with anemia are asymptomatic, and the condition is detected on screening laboratory evaluation. Screening is recommended only for high-risk children. Anemia is classified as...

  • Lesson of the Week: Gastrointestinal investigation of iron deficiency anaemia. Cook, Ian J.; Pavli, Paul; Riley, John W.; Goulston, Kerry J.; Dent, Owen F. // British Medical Journal (Clinical Research Edition);5/24/1986, Vol. 292 Issue 6532, p1380 

    Examines the need for colonic assessment in elderly patients with microcytic iron deficiency anemia and a benign lesion on upper gastrointestinal endoscopy. Measurement of serum iron concentration; Use of non-steroidal anti-inflammatory drugs; Cause of deficiency.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics