TITLE

Continuous microfluidic immunomagnetic cell separation

AUTHOR(S)
Inglis, David W.; Riehn, R.; Austin, R. H.; Sturm, J. C.
PUB. DATE
November 2004
SOURCE
Applied Physics Letters;11/22/2004, Vol. 85 Issue 21, p5093
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We present a continuous-flow microfluidic device that enables cell by cell separation of cells selectively tagged with magnetic nanoparticles. The cells flow over an array of microfabricated magnetic stripes, which create a series of high magnetic field gradients that trap the magnetically labeled cells and alter their flow direction. The process was observed in real time using a low power microscope. The device has been demonstrated by the separation of leukocytes from whole human blood.
ACCESSION #
15155509

 

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