Bioanalytical applications of Raman spectroscopy

Krafft, Christoph
January 2004
Analytical & Bioanalytical Chemistry;Jan2004, Vol. 378 Issue 1, p60
Academic Journal
The article focuses on bioanalytical applications of Raman spectroscopy. In the last two decades Raman spectroscopy has developed into one of the most powerful techniques in biopolymer research. Raman spectra of biological molecules contain numerous bands representing molecular normal modes of vibration and serve as sensitive and selective fingerprints of their structure, composition, interactions, and dynamics. As any pathological condition is accompanied by changes in molecular composition and/or molecular structure in affected tissues or cells and these changes are reflected in the spectra, Raman spectroscopy also has prospects as an analytical tool in medical science.


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