Miniaturized liquid separation techniques in bioanalysis

Holland, Lisa A.; McKeon, Jocelyn
January 2004
Analytical & Bioanalytical Chemistry;Jan2004, Vol. 378 Issue 1, p40
Academic Journal
The article focuses on liquid separation techniques in bioanalysis. The list of biologically relevant analytes is diverse: biopolymers like DNA, RNA, protein, carbohydrate, biomonomers: amino acids, nucleic acids, monosaccharides, lipids, and other molecules. The drive for core information in kinetics, thermodynamics, and composition provides the ability to answer diverse questions related to mechanism, function, purpose, design, disruption, or interruption of biological processes. The miniaturized liquid-based separations currently pushing the frontier of bioanalytical microseparations are capillary electrophoresis, capillary liquid chromatography and capillary electrochromatography.


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