Bioimprinted QCM sensors for virus detection—screening of plant sap

Dickert, Franz L.; Hayden, Oliver; Bindeus, Roland; Mann, Karl-J.; Blaas, Dieter; Waigmann, Elisabeth
April 2004
Analytical & Bioanalytical Chemistry;Apr2004, Vol. 378 Issue 8, p1929
Academic Journal
Surface imprinting techniques on polymer-coated quartz-crystal microbalances (QCM) have been used to detect tobacco mosaic viruses (TMV) in aqueous media. Molecularly imprinted polymers (MIP), tailor-made by self organisation of monomers around a template (TMV), were generated directly on the gold electrodes. Imprinted trenches on the polymer surface mimicking the shape and surface functionality of the virus serve as recognition sites for re-adsorption after washing out of the template. The sensors are applicable to TMV detection ranging from 100 ng mL-1 to 1 mg mL-1 within minutes. Furthermore, direct measurements without time-consuming sample preparation are possible in complex matrices such as tobacco plant sap.


Related Articles

  • Solution properties of charged quasi-random copolymers: Integral equation theory. Zherenkova, Lubov V.; Khalatur, Pavel G.; Khokhlov, Alexei R. // Journal of Chemical Physics;10/1/2003, Vol. 119 Issue 13, p6959 

    Using the polymer integral equation method, we study the solution properties of charged quasi-random two-letter (HP) copolymers with two different types of distribution of monomer units along a copolymer chain: proteinlike copolymers and random-block copolymers. The copolymers consist of monomer...

  • REACH Update: Bulk Registration, Polymers, Consortia and More. Struessman, Annelie // Cosmetics & Toiletries;Oct2008, Vol. 123 Issue 10, p10 

    The article presents an update for the previous issue related to the procedures of Registration, Evaluation and Authorization of Chemical (REACH) published by European Chemical Agency (ECHA) in Europe. The update includes the pre-registration recommended, bulk registration and monomers and polymers.

  • The escape transition of a polymer: A unique case of non-equivalence between statistical ensembles. Dimitrov, D. I.; Klushin, L. I.; Skvortsov, A.; Milchev, A.; Binder, K. // European Physical Journal E -- Soft Matter;May2009, Vol. 29 Issue 1, p9 

    A flexible polymer chain under good solvent conditions, end-grafted on a flat repulsive substrate surface and compressed by a piston of circular cross-section with radius L may undergo the so-called “escape transition” when the height of the piston D above the substrate and the chain...

  • Preparation of a novel molecularly imprinted polymer using a water-soluble crosslinking agent. Kubo, Takuya; Hosoya, Ken; Nomachi, Makoto; Tanaka, Nobuo; Kaya, Kunimitsu // Analytical & Bioanalytical Chemistry;Aug2005, Vol. 382 Issue 7, p1698 

    A molecularly imprinted polymer was prepared using a water-soluble crosslinking agent. An ionic complex was utilized as the assembly for the template molecule and the functional monomer, and water as porogenic solvent during preparation of the imprinted polymer. The results of chromatographic...

  • Inclusion and Functionalization of Polymers with Cyclodextrins: Current Applications and Future Prospects. Folch-Cano, Christian; Yazdani-Pedram, Mehrdad; Olea-Azar, Claudio // Molecules;Sep2014, Vol. 19 Issue 9, p14066 

    The numerous hydroxyl groups available in cyclodextrins are active sites that can form different types of linkages. They can be crosslinked with one another, or they can be derivatized to produce monomers that can form linear or branched networks. Moreover, they can form inclusion complexes with...

  • Kerr Effect in the Isotropic Phase of Copolymers with Mesogenic Side Groups. Polushin, S.; Filippov, S.; Barmatov, E.; Pebalk, D.; Rjumtsev, E. // Doklady Physical Chemistry;Dec2005, Vol. 405 Issue 4-6, p257 

    The article examines the isotropic phase of copolymers with mesogenic side groups by the transient electric birefringence (TEB, the Kerr effect) method. Mesogen is responsible for the formation liquid-crystalline phase. Functional monomer imparts the desired physicochemical properties to...

  • Kinetics of microphase separation in interpenetrated polymer networks in solution. Derouiche, A.; Benhamou, M.; Bettachy, A. // European Physical Journal E -- Soft Matter;Apr2005, Vol. 16 Issue 4, p365 

    We present here a theoretical study of the early kinetics of the microphase separation in crosslinked polymer blends, made of two incompatible polymersAandB, dissolved in a common good solvent. Use is made of an extended blob model used previously for the investigation of the static properties...

  • Polymer brushes near the crystallization density. He, G.-L.; Merlitz, H.; Sommer, J.-U.; Wu, C.-X. // European Physical Journal E -- Soft Matter;Dec2007, Vol. 24 Issue 4, p325 

    In this paper, polymer brushes are studied via molecular-dynamics simulations at very high grafting densities, where the crossover between the brush regime and the polymer-crystal regime is taking place. This crossover is directly observed with the structure factor and pair-correlation function....

  • pol·y·mer.  // American Heritage Student Science Dictionary;2009, p273 

    A definition of the term "polymer" is presented. It refers to any of various chemical compounds made of smaller, identical molecules called monomers linked together. Polymers have extremely high molecular weights, make up many of the tissues of organisms, and are used to make such materials as...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics