TITLE

Direct optical resolution of the enantiomers of novel chiral tetrahedral metal clusters by HPLC on a cellulose tris-(3,5-dimethylphenylcarbamate) stationary phase

AUTHOR(S)
Wenzhi Li; Weiqiang Zhang; Quanyi Zhao; Yongmin Li; Chunlin Ma; Liren Chen; Yuanqi Yin
PUB. DATE
March 2004
SOURCE
Analytical & Bioanalytical Chemistry;Mar2004, Vol. 378 Issue 5, p1364
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The enantioseparation of seven novel chiral transition metal tetrahedral clusters has been achieved for the first time on cellulose derivatized with tris(3,5-dimethylphenylcarbamate) (CDMPC) as chiral stationary phase (CSP) and hexane containing different alcohols as modifiers as mobile phases. The effect of mobile-phase composition on enantioselectivity was studied, and the effect of structural variation of the solutes on their enantioseparation was also investigated. It was found that both the metal in the tetrahedral core and the ligand coordinated to the atom in the tetrahedral core had significant effects on the chromatographic behavior of the analytes.
ACCESSION #
15124881

 

Related Articles

  • Expression, purification and characterization of an iron-sulfur cluster assembly protein, IscU, from Acidithiobacillus ferrooxidans. Jia Zeng; Wenjie Zhao; Yuandong Liu; Lexian Xia; Jianshe Liu; Guanzhou Qiu // Biotechnology Letters;Dec2007, Vol. 29 Issue 12, p1965 

    An iron-sulfur cluster assembly protein, IscU, is encoded by the operon iscSUA in Acidithiobacillus ferrooxidans. The gene of IscU was cloned and expressed in Escherichia coli. The protein was purified by one-step affinity chromatography to homogeneity. The protein was in apo-form, the [Fe2S2]...

  • Peak Tailing and Resolution. Nolan, John W. // LC-GC North America;May2002, Vol. 20 Issue 5, p430 

    Illustrates how a specific resolution value sometimes can be a misleading description of a liquid chromatography separation. Measurement of resolution; Description of peak tailing in chromatography; Effect of tailing peaks on the quality of a separation; Changes in peak size.

  • Critical Pairs in Column Chromatography: A Primer for pharmaceutical Method Validation. Webster, Gregory K.; Basel, Christopher L. // LC-GC North America;Sep2003 Supplement, Vol. 21 Issue 9, p78 

    Evaluates common applications of the critical-pair approach to column chromatography applied under pharmaceutical guidelines and validation strategies. Use of critical pairs to produce separation methods that provide baseline resolution of analyte peaks in short analysis periods; Inclination of...

  • Expression, purification and characterization of a cysteine desulfurase, IscS, from Acidithiobacillus ferrooxidans. Jia Zeng; Yanfei Zhang; Yuandong Liu; Xiaojian Zhang; Leixian Xia; Jianshe Liu; Guanzhou Qiu // Biotechnology Letters;Dec2007, Vol. 29 Issue 12, p1983 

    Iron–sulfur clusters are one of the most common types of redox center in nature. Three proteins of IscS (a cysteine desulfurase), IscU (a scaffold protein) and IscA (an iron chaperon) encoded by the operon iscSUA are involved in the iron–sulfur cluster assembly in Acidithiobacillus...

  • Crossover among structural motifs in transition and noble-metal clusters. Baletto, F.; Ferrando, R.; Fortunelli, A.; Montalenti, F.; Mottet, C. // Journal of Chemical Physics;3/1/2002, Vol. 116 Issue 9, p3856 

    The energetics of nanoclusters is investigated for five different metals (Ag, Cu, Au, Pd, and Pt) by means of quenched molecular dynamics simulations. Results are obtained for two different semiempirical potentials. Three different structural motifs are considered: icosahedra (Ih), decahedra...

  • Troubleshooting GC Selectivity, Resolution, and Baseline Issues.  // LC-GC North America;Aug2013, Vol. 31 Issue 8, p646 

    The article presents information on how to troubleshoot gas chromatography (GC) selectivity, resolution, and baseline issues. Knowing the chemistry behind GC separations can lead to faster problem determination and enhanced troubleshooting. Sudden selectivity changes in GC, fortunately, are...

  • Phytosterol Analysis Using a HyPURITY AQUASTARâ„¢ Column. Phillips, Rachel // LC-GC North America;Sep2003 Supplement, Vol. 21 Issue 9, p75 

    Demonstrates the use of Thermo Electron's HyPURITY AQUASTAR Column for the analysis of phytosterol. Design of the tool to combine bonding, end-capping and silica quality to enable opportunities for the retention, resolution and selectivity of polar analytes; Absence of the need for organic...

  • The Perfect Method, Part 6: Make It Faster. Dolan, John W. // LC-GC Europe;Feb2008, Vol. 21 Issue 2, p78 

    The article examines some of the improved resolution of liquid chromatographers methods for its faster separation. Equation 1 has been used to develop a separation with the necessary resolution, where it will adjust the column parameters to increase or decrease resolution to fit the target value...

  • The Importance of the Sample Matrix. Dolan, John W. // LC-GC Europe;Feb2013, Vol. 26 Issue 2, p92 

    The article discusses the importance of understanding contents of the sample matrix in the chromatographic sample to elute out the analytes of interest with better resolution. It highlights that the appropriate knowledge of the impurities in chromatographic sample is necessary to develop...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics