TITLE

Voltammetric determination of thiodiglycolic acid in urine

AUTHOR(S)
Dlasková, Zdeňka; Navrátil, Tomáś; Heyrovský, Michael; Pelclová, Daniela; Novotný, Ladislav
PUB. DATE
January 2003
SOURCE
Analytical & Bioanalytical Chemistry;Jan2003, Vol. 375 Issue 1, p164
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
In urine the level of thiodiglycolic acid (TDGA) is a sensitive indicator of exposure of the human organism to some physiologically active or toxic substances, gases and vapors. The determination of TDGA by use of a voltammetric method based on electroreduction of TDGA in acidic solution at the hanging mercury drop electrode has been developed and practically tested. In order to eliminate the matrix effect of urine, prior to voltammetric measurement the samples are eluted from a small column of PVC powder. The method is simple, low cost, rapid and sensitive, appropriate for the needs of occupational medicine.
ACCESSION #
15124443

 

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