Giant magnetoresistance monitoring of magnetic picodroplets in an integrated microfluidic system

Pekas, Nikola; Porter, Marc D.; Tondra, Mark; Popple, Anthony; Jander, Albrecht
November 2004
Applied Physics Letters;11/15/2004, Vol. 85 Issue 20, p4783
Academic Journal
This letter describes the integration of giant magnetoresistance (GMR) sensors with a microfluidic system tor the velocity and size monitoring, and enumeration of flowing magnetic entities. We have fabricated a microdevice that enables: (1) controlled formation of picoliter-sized droplets of a ferrofluid separated by a nonmagnetic oil; and (2) continuous-flow sensing of these ferrofluid droplets. It is shown that the flow velocity, droplet size, and droplet-formation frequency can readily he determined from the GMR response. These results are validated by comparisons to fluorescence microscopy data.


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