TITLE

Determination of Glucose Concentration in Whole Blood using Fourier-Transform Infrared Spectroscopy

AUTHOR(S)
Shen, Y.C.; Davies, A.G.; Linfield, E.H.; Taday, P.F.; Arnone, D.D.; Elsey, T.S.
PUB. DATE
April 2003
SOURCE
Journal of Biological Physics;Apr2003, Vol. 29 Issue 2/3, p129
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Fourier-transform infrared (FTIR) transmission spectroscopy has been used for the determination of glucose concentrations in whole blood samples from twenty-eight patients. A four-vector partial least squares calibration model, using the spectral range 950–1200 cm-1, yielded a standard error of prediction of 0.59 mM for an independent test set. For blood samples from a single patient, we found that the glucose concentration was proportional to the difference between the values of the second derivative spectrum at 1082 cm-1 and 1093 cm-1, suggesting that these two specific wavelengths can be used for determining glucose concentrations in blood.
ACCESSION #
14990864

 

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