TITLE

Macroscopic characterization of cell electroporation in biological tissue based on electrical measurements

AUTHOR(S)
Cima, Lionel F.; Mir, Lluis M.
PUB. DATE
November 2004
SOURCE
Applied Physics Letters;11/8/2004, Vol. 85 Issue 19, p4520
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
A method is described to experimentally determine the temporal evolution of state variables involved in the electroporation of biological tissue, i.e., the transmembrane voltage and the macroscopic current flowing in the electropores. Indeed, the electrical parameters of the extracellular, intracellular, and unaltered membrane contributions as well as the electropores electrical characteristics can be deduced from the measurement of the tissue bioimpedance and from the variations of both the macroscopic voltage applied to the tissue and the delivered current.
ACCESSION #
14974928

 

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