TITLE

The electrochemistry and determination of Ligustrazine hydrochloride

AUTHOR(S)
Sun, Ziyi; Xiaofeng Zheng; Hoshi, Tomonori; Kashiwagi, Yoshitomo; Anzai, Jun-ichi; Genxi Li
PUB. DATE
October 2004
SOURCE
Analytical & Bioanalytical Chemistry;Oct2004, Vol. 380 Issue 3, p545
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Ligustrazine is one of the active ingredients contained inLigusticum chuanxiongHort. (Umbelliferae), which is widely used in traditional Chinese medicine for the treatment of cardiovascular problems. In this work, the electrochemistry of Ligustrazine hydrochloride (LZC) and its determination are investigated. The detection limit is estimated to be 8.0×10-8 M, with three linear ranges from 1.0×10-6 to 1.0×10-4 M, 1.0×10-4 to 5.0×10-4 M, and 6.5×10-4 to 1.6×10-3 M. The method has been proved to be highly sensitive, selective, and stable, and has been successfully applied to determining LZC in LZC injections.
ACCESSION #
14854107

 

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