Bleeding Disorder Basics

Curry, Heather
September 2004
Pediatric Nursing;Sep/Oct2004, Vol. 30 Issue 5, p402
Academic Journal
This article focuses on bleeding disorders. The most common genetic bleeding disorder is von Willebrand Disease. Its presence is determined by a gene on chromosome 12. Occasionally it occurs as a new mutation. It affects up to 3% of the world's population, all genders and races. The von Willebrand factor is a protein with two functions necessary for hemostasis. One function is to bind to factor VIII as it circulates in the blood, protecting it from degradation. The second function is to act as glue to attach platelets to the blood vessel wall at the site of injury


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