TITLE

Risk factors for intracardiac thrombus in patients with recent ischaemic cerebrovascular events

AUTHOR(S)
Sen, S.; Laowatana, S.; Lima, J.; Oppenheimer, S. M.
PUB. DATE
October 2004
SOURCE
Journal of Neurology, Neurosurgery & Psychiatry;Oct2004, Vol. 75 Issue 10, p1421
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
Background: Intracardiac thrombus is a common cause of cardiogenic cerebral ischaemia. Stroke recurrence is high, but thrombus detection with therapeutic intervention can reduce the risk. Accurate detection requires transoesophageal echocardiography (TOE), which is semi-invasive and costly.Objective: To identify risk factors for cardiac thrombus, enabling selection of patients for TOE and initiation of measures to prevent the formation of cardiac thrombus.Methods: 151 consecutive patients with ischaemic stroke or transient ischaemic attacks (mean age 62 years) underwent TOE for intracardiac thrombus detection within one week of a qualifying event.Results: Intracardiac thrombus was found in 26% of the patients (70% in the left atrial appendage). Multivariate analysis indicated the following clinical correlates: large stroke, odds ratio (OR) = 2.8 (95% confidence interval, 1.2 to 6.4); symptomatic coronary artery disease, OR = 3.0 (1.2 to 7.4); and ECG evidence of ischaemia, OR = 2.8 (1.1 to 7.7). Neither carotid stenosis >70%, nor stroke location correlated with the presence of thrombus.Conclusions: Clinical factors correlate with and appear to be risk factors for cardiac thrombus in patients with recent cerebral ischaemia. These may be used to select appropriate patients for invasive and costly TOE investigation, irrespective of the presence of significant carotid stenosis (>/=70%) or stroke location.
ACCESSION #
14730172

 

Related Articles

  • Metabolic syndrome increases the risk of stroke: a 5-year follow-up study in a Chinese population. Wei-Wei Zhang; Chun-Yu Liu; Yan-Jiang Wang; Zhi-Qiang Xu; Yang Chen; Hua-Dong Zhou // Journal of Neurology;Sep2009, Vol. 256 Issue 9, p1493 

    Limited information is available on the relationship between metabolic syndrome and stroke in the Chinese population. The aim of this study was to establish the prevalence of metabolic syndrome in the Chinese population and the relationship between stroke and metabolic syndrome in that...

  • Evaluation of stroke risk factors among hospitalized patients with ischemic stroke in Baghdad. Hasan, Zaki Noah; Hasan, Hasan Azeez; Mukhelif, Hamed Facker // Iraqi Journal of Medical Sciences;2008, Vol. 6 Issue 1, p99 

    Introduction: Identification of stroke risk factors is of great importance to prevent the disease and its sequels. Objective: Is to analyze the known stroke risk factors and to study the education level, housing condition and economic status as possible relevant stroke risk factors. Patients and...

  • lschaemic stroke subtypes and associated risk factors: a French population based study. Bejot, Y.; Caillier, M.; Salem, D. Ben; Couvreur, G.; Rouaud, O.; Osseby, G-V.; Durier, J.; Marie, C.; Moreau, T.; Giroud, M. // Journal of Neurology, Neurosurgery & Psychiatry;Dec2008, Vol. 79 Issue 12, p1344 

    Background: There is little reliable population based information about the distribution of risk factors among the various ischaemic stroke subtypes, even though determining risk factor profiles is of major importance to develop targeted preventive strategies. Methods: The distribution of first...

  • Sequentially based analysis versus image based analysis of Intima Media Thickness in common carotid arteries studies - Do major IMT studies underestimate the true relations for cardio- and cerebrovascular risk? Sandrock, M.; Hansel, J.; Schulze, J.; Schmitz, D.; Niess, A.; Burkhardt, H.; Schmidt-Trucksaess, A. // Cardiovascular Ultrasound;2008, Vol. 6, Special section p1 

    Background: Image-based B-mode ultrasound has gained popularity in major studies as a noninvasive method of measuring cardio- and cerebrovascular risk factors. However, none of the major studies appears to have paid sufficient attention to the variation in end diastolic wall process. By using...

  • Neighborhood Environment and Risk of Ischemic Stroke. LD Lisabeth; AV Diez Roux; JD Escobar; MA Smith; LB Morgenstern // American Journal of Epidemiology;Feb2007, Vol. 165 Issue 3, p279 

    The authors explored whether neighborhood-level characteristics are associated with ischemic stroke and whether the association differs by ethnicity, age, and gender. Using data from the Brain Attack Surveillance in Corpus Christi Project (January 2000–June 2003), they identified cases of...

  • RESEARCH BRIEF: Statins reduce the risk of stroke.  // GP: General Practitioner;3/8/2004, p10 

    A five-year Great Britain study involving 20,536 patients at a high risk of stroke found that patients taking 40 mg simvastatin daily had a 25 percent lower stroke risk, compared to those who were taking placebo. The risk of ischaemic stroke was reduced by 30 percent.

  • British Geriatrics Society.  // Age & Ageing;Sep95 Supplement 2, Vol. 24, pP15 

    Presents an abstract of the study `Coagulation factors in acute stroke and transient ischaemic attacks,' by P.B. Khanna, B.K. Bhowmick and J. Kassab, presented during the spring meeting of the British Geriatrics Society on April 6 to 8, 1995.

  • Awareness of stroke and stroke outcomes. Inzitari, D. // Neurological Sciences;Apr2006, Vol. 27 Issue 1, p1 

    The article cites research findings on the assessment of the awareness about ischaemic stroke among certain groups of people who have a high risk for the disease. Key issues discussed include the test subjects' lack of knowledge regarding the risk factors that predispose them to stroke and their...

  • Risk factors and prognosis of young stroke. The FUTURE study: A prospective cohort study. Study rationale and protocol.  // BMC Neurology;2011, Vol. 11 Issue 1, p109 

    The article presents information on a prospective cohort study the FUTURE study, on the risk factors and prognosis of young ischemic and hemorrhagic stroke. The study was conducted on 1006 patients that are aged between 18-50 years. It is stated that the study has the potential to make...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics