TITLE

Electromagnetic needles with submicron pole tip radii for nanomanipulation of biomolecules and living cells

AUTHOR(S)
Matthews, Benjamin D.; LaVan, David A.; Overby, Darryl R.; Karavitis, John; Ingber, Donald E.
PUB. DATE
October 2004
SOURCE
Applied Physics Letters;10/4/2004, Vol. 85 Issue 14, p2968
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We describe the design and fabrication of a temperature-controlled electromagnetic microneedle (EMN) to generate custom magnetic field gradients for biomedical and biophysical applications. An electropolishing technique was developed to sharpen the EMN pole tip to any desired radius between 100 nm and 20 μm. The EMN can be used to apply strong static or dynamic forces (>50 nN) to micrometer- or nanometer-sized magnetic beads without producing significant heating or needle movement. Large tip radii (20 μm) allow magnetic force application to multiple magnetic beads over a large area, while small radii (0.1–6 μm) can be used to selectively pull or capture single magnetic beads from within a large population of similar particles. The customizable EMN is thus well suited for micro- and nanomanipulation of magnetic particles linked to biomolecules or living cells.
ACCESSION #
14713324

 

Related Articles

  • Inversed tunneling magnetoresistance in hybrid FePt/Fe3O4 core/shell nanoparticles systems. Yunpeng Zhang; Hui Xing; Poudyal, Narayan; Nandwana, Vikas; Chuan-bing Rong; Shi-shen Yan; Hao Zeng; Liu, J. P. // Journal of Applied Physics;Nov2010, Vol. 108 Issue 10, p103905 

    Magnetotransport studies were performed on hybrid FePt/Fe3O4 core/shell nanoparticle systems. The linear relationship of LnR versus T-1/2 with and without a magnetic field confirms the physical picture of thermally assisted interparticle tunneling. A sign inversion of tunneling magnetoresistance...

  • Low cost Nano-membrane Fabrication and Electro-polishing System.  // World Academy of Science, Engineering & Technology;Apr2010, Issue 40, p56 

    No abstract available.

  • Magnetic fields and fluxes probed by coherent low-energy electron beams. Degiovanni, Alain; Bardon, Jacques; Georges, Vincent; Morin, Roger // Applied Physics Letters;10/4/2004, Vol. 85 Issue 14, p2938 

    The magnetization of a nanometer size Ni needle is observed using the coherent electron beam originating from an electron point source. This at one and the same time displays the local (Lorentz force) and the nonlocal (Aharonov–Bohm phase shift) magnetic effects. The experiments are...

  • Self-heating property under ac magnetic field and its evaluation by ac/dc hysteresis loops of NiFe2O4 nanoparticles. Kobayashi, H.; Hirukawa, A.; Tomitaka, A.; Yamada, T.; Jeun, M.; Bae, S.; Takemura, Y. // Journal of Applied Physics;May2010, Vol. 107 Issue 9, p09B322-1 

    The temperature rise of NiFe2O4 nanoparticles having diameters of 242 and 7.7 nm was measured. The results of the measurement were analyzed by comparing the areas of the hysteresis loops in order to clarify the mechanism of heat dissipation in the samples. The hysteresis loops were obtained by...

  • Spin-dependent Peltier effect in Co/Cu multilayer nanowires. Gravier, Laurent; Serrano-Guisan, Santiago; Ansermet, J.-Ph. // Journal of Applied Physics;5/15/2005, Vol. 97 Issue 10, p10Q513 

    Heat transport perpendicular to the plane of magnetic multilayers is monitored with ac temperature gradients in the presence of a direct charge current. A very strong dependence on the applied magnetic field of the voltage response to the ac gradient is observed using Co/Cu multilayered...

  • MBE growth and characterization of MnP and Ge nanowhiskers. Bouravleuv, A. D.; Minami, K.; Sato, Y.; Ishibashi, T.; Sato, K. // AIP Conference Proceedings;2007, Vol. 893 Issue 1, p57 

    Ge and MnP nanowhiskers have been grown by molecular beam epitaxy (MBE) concurrently on InP and GaAs substrates. The growth of MnP nanowhiskers appears to be caused by catalytic free growth mechanism, whereas the growth of Ge nanowhiskers is found to be amenable to vapour-liquid-solid (VLS)...

  • Control of spin configuration in half-metallic La0.7Sr0.3MnO3 nano-structures. Rhensius, J.; Vaz, C. A. F.; Bisig, A.; Schweitzer, S.; Heidler, J.; Körner, H. S.; Locatelli, A.; Niño, M. A.; Weigand, M.; Méchin, L.; Gaucher, F.; Goering, E.; Heyderman, L. J.; Kläui, M. // Applied Physics Letters;8/8/2011, Vol. 99 Issue 6, p062508 

    We investigate the interplay between the governing magnetic energy terms in patterned La0.7Sr0.3MnO3 (LSMO) elements by direct high-resolution x-ray magnetic microscopy as a function of temperature and geometrical parameters. We show that the magnetic configurations evolve from multidomain to...

  • Abnormal magnetic behaviors and large magnetocaloric effect in MnPS3 nanoparticles. Zeng, R.; Wang, S. Q.; Du, G. D.; Wang, J. L.; Debnath, J. C.; Shamba, P.; Fang, Z. Y.; Dou, S. X. // Journal of Applied Physics;Apr2012, Vol. 111 Issue 7, p07E144 

    A nanostructured honeycomb lattice consisting of MnPS3 nanoparticles synthesized via the ion-exchange technique was found to have restacked molecular layers stabilized by H2O insertion between the layers. Susceptibility (χ) and heat capacity measurements showed the absence of long range...

  • Magnetoresistance in Sn-Doped In2O3 Nanowires. Berengue, Olívia M.; Lanfredi, Alexandre J. C.; Pozzi, Livia P.; Rey, José F. Q.; Leite, Edson R.; Chiquito, Adenilson J. // Nanoscale Research Letters;Aug2009, Vol. 4 Issue 8, p921 

    In this work, we present transport measurements of individual Sn-doped In2O3 nanowires as a function of temperature and magnetic field. The results showed a localized character of the resistivity at low temperatures as evidenced by the presence of a negative temperature coefficient resistance in...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics