Vestibular Toxicity Due to Inhaled Tobramycin in a Patient With Renal Insufficiency
- Clinical manifestation of macrolide antibiotic toxicity in CKD and dialysis patients. Ma, Terry King-Wing; Chow, Kai-Ming; Choy, Agnes Shin Man; Kwan, Bonnie Ching-Ha; Szeto, Cheuk-Chun; Li, Philip Kam-Tao // Clinical Kidney Journal;Dec2014, Vol. 7 Issue 6, p507
Macrolide antibiotics, erythromycin, clarithromycin and azithromycin are commonly prescribed for upper respiratory infection, and their use has recently been further linked to immunomodulatory effects. With the widespread and expanded use of macrolides, special attention should be paid to their...
- Ethchlorvynol (Placidyl) Intoxication. Westervelt Jr., Frederic B. // Annals of Internal Medicine;Jun66, Vol. 64 Issue 6, p1229
Presents case studies on the toxic side effects of ethchlorvynol treatment. Medical history of the patients; Relationship of barbiturate intake and the severity of coma; Metabolic disposal mechanisms of ethchlorvynol.
- Amikacin-induced type 5 Bartter-like syndrome with severe hypocalcemia. Chrispal, A.; Boorugu, H.; Prabhakar, A. T.; Moses, V. // Journal of Postgraduate Medicine;Sep2009, Vol. 55 Issue 3, p208
Aminoglycoside-induced renal toxicity is well known and may manifest with nonoliguric renal failure or renal tubular dysfunction. Aminoglycoside-induced renal tubular dysfunction could result in diffuse damage or manifest as a Fanconi-like syndrome, Bartter-like syndrome, or distal renal tubular...
- Chronic kidney disease in pregnancy. // Journal of Renal Nursing;Mar2013, Vol. 5 Issue 2, p106
The article reports that the inverse relation of renal function and increased proteinuria and hypertension leads to chronic kidney disease (CKD) in pregnant women.
- Importance of Dental Surgeon and Renal Physician Interaction. Chidambaram, Ramasamy // Malaysian Journal of Medical Sciences;Jan/Feb2015, Vol. 22 Issue 1, p89
A letter to the editor is presented related to importance of interaction between dental surgeon and renal physician as patients with chronic kidney disease display variety of oral symptoms.
- The Modern Spectrum of Rhabdomyolysis: Drug Toxicity Revealed by Creatine Kinase Screening. Linares, Leslie A.; Golomb, Beatrice A.; Jaojoco, Joyce A.; Sikand, Harminder; Phillips, Paul S. // Current Drug Safety;Sep2009, Vol. 4 Issue 3, p181
Purpose: This study describes the current etiologies, demographic characteristics, incidence of acute renal insufficiency and correlation between peak creatine kinase (CK) and peak creatinine in hospitalized patients with rhabdomyolysis. Methods: A retrospective chart review of patients with...
- An approach for cloning biosynthetic genes of 2-deoxystreptamine-containing aminocyclitol antibiotics: isolation of a biosynthetic gene cluster of tobramycin from Streptomyces tenebrarius. Kharel, Madan Kumar; Subba, Bimala; Lee, Hei Chan; Liou, Kwangkyoung; Woo, Jin Suk; Sohng, Jae Kyung // Biotechnology Letters;Dec2003, Vol. 25 Issue 24, p2041
Genes homologous to 2-deoxystreptamine (DOS) biosynthetic genes were isolated from aminoglycoside producers, Micromonospora and Streptomyces spp., using PCR primers based on the core sequences of 2-deoxy-scyllo-inosose (DOI) synthase and l-glutamine: scyllo-inosose aminotransferase (GIA)....
- Resonance Rayleigh scattering spectra for studying the interaction of aminoglycoside antibiotics with pontamine sky blue and their analytical applications. Hu, Xiaoli L.; Liu, Shaopu P.; Li, Nianbing // Analytical & Bioanalytical Chemistry;May2003, Vol. 376 Issue 1, p42
In a weakly acid medium, some aminoglycoside antibiotics, such as kanamycin (KANA), gentamicin (GEN), tobramycin (TOB), and neomycin (NEO), or acid bisazo dye pontamine sky blue (PSB) can only produce very weak resonance Rayleigh scattering (RRS) signals. However, when the two agents react with...
- The Effect of PAMAM Dendrimers on the Antibacterial Activity of Antibiotics with Different Water Solubility. Winnicka, Katarzyna; Wroblewska, Magdalena; Wieczorek, Piotr; Tomasz Sacha, Pawel; Tryniszewska, Elzbieta Anna // Molecules;Jul2013, Vol. 18 Issue 7, p8607
Erythromycin (EM) and tobramycin (TOB) are well-known and widely used antibiotics, belonging to different therapeutic groups: macrolide and aminoglycoside, respectively. Moreover, they possess different solubility: EM is slightly soluble and TOB is freely soluble in water. It was previously...