October 2004
Gut;Oct2004, Vol. 53 Issue 10, p1543
Academic Journal
This article presents summary of articles, related to gastroenterology, published in several journals. The efficacy of proton pump inhibitor therapy in non-ulcer dyspepsia (NUD) is controversial. Researchers have conducted a randomised controlled trial comparing lansoprazole 30 mg once daily, lansoprazole 15 mg once daily, or placebo for eight weeks in 921 NUD patients. Increased waist circumference is the most critical index of obesity that is strongly associated with insulin resistance and its metabolic consequences. Although both abdominal subcutaneous fat mass as well as visceral fat contribute to central obesity, it is not known whether one or both of the fat depots are involved in the pathogenesis of insulin resistance.


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