EDITOR'S QUIZ: CI SNAPSHOT: A rare cause of gastrointestinal bleeding in a patient with hyper-IgE syndrome

Götzberger, M.; Schlesinger, A.; Dauer, M.; Heldwein, W.; Jansson, A.; Renner, E.; Belohradsky, B. H.
October 2004
Gut;Oct2004, Vol. 53 Issue 10, p1430
Academic Journal
This article discusses about mycobacterial infections. Mycobacterium genavense is a newly recognised non-tuberculous mycobacteria (NTM) that is found mainly in patients with acquired immunodeficiency syndrome and regularly affects the digestive tract. Intestinal infections due to NTM are known to mimic Whipple's disease endoscopically and histologically. Ulcerative lesions affecting the large bowel and causing gastrointestinal bleeding represent a rare endoscopic finding. Mycobacterial infections are uncommon complications in patients with hyper-IgE syndrome and treatment experiences are limited for this NTM species. Treatment was begun with a multidrug regimen of rifabutin, ethambutol, clarithromycin, and ciproflocazin. Three month follow up revealed regression of duodenal defects and normal mucosa on colonoscopy, indicating, to date, an adequate response to therapy.


Related Articles

  • Colorectal endoscopic submucosal dissection (ESD) performed by experienced endoscopists with limited experience in gastric ESD. Shiga, Hisashi; Kuroha, Masatake; Endo, Katsuya; Kimura, Tomoya; Kakuta, Yoichi; Kinouchi, Yoshitaka; Kayaba, Shoichi; Shimosegawa, Tooru // International Journal of Colorectal Disease;Dec2015, Vol. 30 Issue 12, p1645 

    Purpose: Since colorectal endoscopic submucosal dissection (ESD) requires higher-level skills than endoscopic mucosal resection (EMR), it is recommended to acquire sufficient experience in gastric ESD prior to attempting colorectal ESD. We evaluated the ability of experienced endoscopists with...

  • Significant Depletion of CD4+ T Cells Occurs in the Oral Mucosa during Simian Immunodeficiency Virus Infection with the Infected CD4+ T Cell Reservoir Continuing to Persist in the Oral Mucosa during Antiretroviral Therapy. George, Jeffy; Wagner, Wendeline; Lewis, Mark G.; Mattapallil, Joseph J. // Journal of Immunology Research;4/30/2015, Vol. 2015, p1 

    Human and simian immunodeficiency virus (HIV and SIV) infections are characterized by manifestation of numerous opportunistic infections and inflammatory conditions in the oral mucosa. The loss of CD4+ T cells that play a critical role in maintaining mucosal immunity likely contributes to this...

  • Endoscopy.  // Current Medical Literature: Gastroenterology;2011, Vol. 30 Issue 4, p132 

    The article discusses several studies related to endoscopy. "Endoscopic Mucosal Resection Outcomes and Prediction of Submucosal Cancer from Advanced Colonic Mucosal Neoplasia," by A. Moss, et al. "Development and Validation of a Novel Patient Educational Booklet to Enhance Colonoscopy...

  • Colonic Chicken Skin Mucosa: Association With Juvenile Polyps in Children. Nowick, Michael J.; Subramony, Cham; Bishop, Phyllis R.; Parker, Paul H. // American Journal of Gastroenterology;Mar2001, Vol. 96 Issue 3, p788 

    OBJECTIVES: Chicken skin mucosa is a newly described endoscopic finding associated with colonic neoplasms in adults. Chicken skin mucosa was sought in children with juvenile polyps to determine the prevalence, endoscopic features, and location. An alternative theory is proposed for the...

  • Evaluation of Mucosal Healing of Ulcerative Colitis by a Quantitative Fecal Immunochemical Test. Nakarai, Asuka; Kato, Jun; Hiraoka, Sakiko; Kuriyama, Motoaki; Akita, Mitsuhiro; Hirakawa, Tomoko; Okada, Hiroyuki; Yamamoto, Kazuhide // American Journal of Gastroenterology;Jan2013, Vol. 108 Issue 1, p83 

    OBJECTIVES:Accumulating evidence has underlined the importance of mucosal healing as a treatment goal for ulcerative colitis (UC). Quantitative fecal immunochemical tests (FITs), which can rapidly quantify fecal blood with automated equipment, have been used recently to screen for colorectal...

  • PROSPECTIVE AUDIT OF THE INCIDENCE OF PREPARATION COLITIS ASSOCIATED WITH SODIUM PHOSPHATE. Weaver, S. A.; Ainley, E. J.; Hickling, M.; Lesna, M.; Guha, N.; Winwood, P. J.; McCullen, M. A. // Gut;Apr2004 Supplement 3, Vol. 53, pA47 

    This article focuses on a study related to prospective audit of the incidence of preparation colitis associated with sodium phosphate (NaP). NaP is a common and effective preparation for colonoscopy. However, it has been reported as causing transient mucosal ulcers of no clinical significance....

  • Diagnostic Value of Small Bowel Capsule Endoscopy in Isolated Ileitis: A CAPENTRY Study. Lee, Hyun; Lim, Yun; Shim, Ki; Moon, Chang; Song, Hyun; Kim, Jin; Jeon, Seong; Jung, Dae; Kim, Ji; Kim, Kyeong; Lee, Bo-In; Lee, Hyun Seok; Lim, Yun Jeong; Shim, Ki Nam; Moon, Chang Mo; Song, Hyun Joo; Kim, Jin Oh; Jeon, Seong Ran; Jung, Dae Young; Kim, Ji Hyun // Digestive Diseases & Sciences;Jan2017, Vol. 62 Issue 1, p180 

    Background: Capsule endoscopy (CE) has proven to be highly effective at detecting small bowel lesions, but studies regarding the diagnostic impact of CE on ileitis are rare.Aims: We evaluated the diagnostic value of small bowel CE for isolated ileitis observed during...

  • Unknown Complicated Celiac Disease as an Unexpected Finding in Patients Investigated with Capsule Endoscopy for Crohn's Disease. A Case Series. Ciobanu, Lidia; Pascu, Oliviu; Iobagiu, Silviu; Damian, Dana; Dumitru, Eugen; Tantau, Marcel // Journal of Gastrointestinal & Liver Diseases;Mar2013, Vol. 22 Issue 1, p97 

    Atypical symptoms of celiac disease may cause a late diagnosis, revealed by the onset of complications, which may inaccurately be attributed to Crohn's disease, as manifestations frequently overlap. Assessing the entire small bowel mucosa, capsule endoscopy may be an accurate procedure in these...

  • HIV Type 1 Infection in Women: Increased Transcription of HIV Type 1 in Ectocervical Tissue Explants. Asin, Susana N.; Eszterhas, Susan K.; Rollenhagen, Christiane; Heimberg, Alysha M.; Howell, Alexandra L. // Journal of Infectious Diseases;9/15/2009, Vol. 200 Issue 6, p965 

    Background. Mucosal surfaces of the female reproductive tract are the main routes of heterosexual transmission of human immunodeficiency virus type 1 (HIV-1), but the contribution of each of the reproductive sites to mucosal transmission is unknown. Methods. We compared levels of HIV-1...


Read the Article


Sign out of this library

Other Topics