Respiratory muscle fibres: specialisation and plasticity

Polio, B.; D'Anlona, G.; Bottinelli, R.; Reggiani, C.
September 2004
Thorax;Sep2004, Vol. 59 Issue 9, p808
Academic Journal
The article presents an overview of the functioning of respiratory muscle fibres in the human body. Muscle fibres are not equal and the ability to generate force and mechanical power, the time course of the contractile response, and the resistance to fatigue differ markedly from fibre to fibre. It discusses several issues such as the types of fibres in the respiratory muscles, perinatal development in humans, contractile activity modifying muscle fibre size and type, effects of ageing on skeletal muscles, diseases affecting respiratory muscles such as muscular dystrophies and their treatment through glucocorticoids and beta agonists, and so on.


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