Progress towards global poliomyelitis eradication: preparation for the oral poliovirus vaccine cessation era

September 2004
Weekly Epidemiological Record;9/24/2004, Vol. 79 Issue 39, p349
The article presents information on the progress towards global poliomyelitis eradication and preparation for the oral poliovirus vaccine cessation era. A substantial body of research has been compiled since 1988 to assist in long-term strategy development, culminating in 2003, when a WHO consultation on circulating vaccine-derived polioviruses concluded that routine use of OPV must be discontinued. The consultation recommended that a strategy be developed for safely stopping OPV use as soon as possible after interruption of transmission, when population immunity is expected to be high and before surveillance sensitivity has started to decline. The experts highlighted the need to consider and manage the potential risks associated with stopping OPV. INSET: Risk Estimates of paralytic disease caused by poliovirus....


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