Review: Tegaserod prompts global relief of symptoms in the irritable bowel syndrome

Irvine, E. Jan
September 2004
ACP Journal Club;Sep/Oct2004, Vol. 141 Issue 2, p44
Academic Journal
This article focuses on the usage of tegaserod in treatment of Irritable Bowel Syndrome (IBS). The rates of response from reference group patients of relief were greater in the tegaserod groups (at each dose and with both doses combined) than in the corresponding placebo groups. Most patients had already been treated with fiber or bulking agents, and given the duration of disease (8 to 16 y) in the study populations, it is likely that these patients were particularly refractory to IBS therapy. Thus tegaserod is more effective than placebo for reducing some symptoms in women with the constipation predominant irritable bowel syndrome.


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