Review: Helicobacter pylori eradication therapy is mildly effective for reducing symptoms in nonulcer dyspepsia

Sharma, Prateek
September 2004
ACP Journal Club;Sep/Oct2004, Vol. 141 Issue 2, p41
Academic Journal
This article presents an update of the cochrane systematic review of helicobacter pylori eradication therapy in Nonulcer Dyspepsia (NUD). In patients with nonulcer dyspepsia and a eradication therapy is mildly effective for reducing dyspepsia symptoms. Although controversial, the widely accepted definition of dyspepsia excludes predominant reflux symptoms. In contrast to the previous meta-analysis, researchers included 2 positive trials of patients having reflux symptoms, including 1 large trial of almost 700 patients with NUD in which eradication therapy showed a benefit.


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