TITLE

Hepatic and splenic amyloidosis: dual-phase spiral CT findings

AUTHOR(S)
Mainenti, P. P.; D'Agostino, L.; Soscia, E.; Romano, M.; Salvatore, M.
PUB. DATE
September 2003
SOURCE
Abdominal Imaging;Sep/Oct2003, Vol. 28 Issue 5, p688
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Although the liver and spleen are frequently involved in primary systemic amyloidosis, the clinical manifestations of hepatic and splenic involvement are usually mild and a dominant symptomatic hepatic presentation is uncommon. We report a case of a 51-year-old woman with giant hepatomegaly, hypertransaminasemia, increase in alkaline phosphatase, and ascites, in whom the findings of dual-phase spiral computed tomography suggested liver and splenic amyloidosis.
ACCESSION #
14555596

 

Related Articles

  • Amyloidosis of lacrimal gland. Prabhakaran, Venkatesh C.; Babu, Kalpana; Mahadevan, Anitha; Murthy, Sowmya Raveendra // Indian Journal of Ophthalmology;Dec2009, Vol. 57 Issue 6, p461 

    Primary localized amyloidosis of lacrimal gland is a rare occurrence. This report describes a female patient with isolated amyloidosis of the lacrimal gland. A 45-year-old Indian woman presented with a swelling over the left lacrimal gland region. Computed tomography showed uniform enlargement...

  • Utility of F-FDG PET(/CT) in patients with systemic and localized amyloidosis. Glaudemans, Andor; Slart, Riemer; Noordzij, Walter; Dierckx, Rudi; Hazenberg, Bouke // European Journal of Nuclear Medicine & Molecular Imaging;Jul2013, Vol. 40 Issue 7, p1095 

    Purpose: Amyloidosis is a group of diseases characterized by deposition of fibrils and this deposition may be localized or systemic. The presence of giant cells is typical of localized AL amyloidosis in contrast to systemic amyloidosis. Because of this presence of giant cells we hypothesize that...

  • Skin Involvement in Generalized Amyloidosis. Rubinow, Alan; Cohen, Alan S. // Annals of Internal Medicine;Jun78, Vol. 88 Issue 6, p781 

    Provides information on a study which examined clinically involved and uninvolved skin in 50 patients with primary and secondary amyloidosis. Description of primary and multiple myeloma-associated amyloidosis; Extent of amyloid involvement in skin biopsies in primary and multiple...

  • Primary localized amyloidosis of the urinary bladder. Kato, Hiroki; Toei, Hisao; Furuse, Makoto; Suzuki, Kazumi; Hironaka, Mitsugu; Saito, Ken // European Radiology;Dec2003 Supplement 4, Vol. 13, pL109 

    We report a rare case of localized form of primary amyloidosis (amyloidoma) of the urinary bladder with CT and MR findings. Clinically, it is difficult to distinguish from invasive transitional cell carcinoma and inflammatory lesion. We think that the MR intensity on T2-weighted images is...

  • Imaging cardiac amyloidosis: a pilot study using F-florbetapir positron emission tomography. Dorbala, Sharmila; Vangala, Divya; Semer, James; Strader, Christopher; Bruyere, John; Carli, Marcelo; Moore, Stephen; Falk, Rodney // European Journal of Nuclear Medicine & Molecular Imaging;Sep2014, Vol. 41 Issue 9, p1652 

    Purpose: Cardiac amyloidosis, a restrictive heart disease with high mortality and morbidity, is underdiagnosed due to limited targeted diagnostic imaging. The primary aim of this study was to evaluate the utility of F-florbetapir for imaging cardiac amyloidosis. Methods: We performed a pilot...

  • Small Transthyretin (TTR) Ligands as Possible Therapeutic Agents in TTR Amyloidoses. Almeida, M. R.; Gales, L.; Damas, A. M.; Cardoso, I.; Saraiva, M. J. // Current Drug Targets - CNS & Neurological Disorders;Oct2005, Vol. 4 Issue 5, p587 

    In transthyretin (TTR) amyloidosis TTR variants deposit as amyloid fibrils giving origin, in most cases, to peripheral polyneuropathy, cardiomyopathy, carpal tunnel syndrome and/or amyloid deposition in the eye. More than eighty TTR variants are known, most of them being pathogenic. The...

  • Typing of Amyloidosis in Renal Biopsies: Diagnostic Pitfalls. Satoskar, Anjali A.; Burdge, Kelly; Cowden, Daniel J.; Nadasdy, Gyongyi M.; Hebert, Lee A.; Nadasdy, Tibor // Archives of Pathology & Laboratory Medicine;Jun2007, Vol. 131 Issue 6, p917 

    Context.—Amyloidosis represents a group of diseases with extracellular deposition of congophilic fibrils of similar morphology but differing chemical composition. The types commonly involving the kidney are AL (light chain amyloid) and AA (serum amyloid A). Familial amyloidosis can also...

  • Pilot Study of the Reducing Effect on Amyloidosis In Vivo by Three FDA Pre-Approved Drugs Via the Alzheimer's APP 5'Untranslated Region. Tucker, Stephanie; Ahl, Michelle; Bush, Ashley; Westaway, David; Xudong Huang; Rogers, Jack T. // Current Alzheimer Research;Apr2005, Vol. 2 Issue 2, p249 

    A pilot study was conducted employing a well known mouse model for Alzheimer's disease to evaluate the anti-amyloid efficacy of three FDA pre-approved drugs. Paroxetine (SSRI and APP 5'UTR directed lead compound), Nacetyl cysteine (antioxidant), and erythromycin (macrolide antibiotic) were...

  • 'Hypersynchronisation' by tissue velocity imaging in patients with cardiac amyloidosis. D Bellavia // Heart;Feb2009, Vol. 95 Issue 3, p234 

    OBJECTIVE: It is unknown if some patients with cardiac amyloidosis (CA) have mechanical dyssynchrony, as has been demonstrated in patients with ischaemic and dilated cardiomyopathies. The aim of this study was to assess mechanical dyssynchrony in patients with CA using tissue velocity imaging...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics