Fats and figures

September 2004
Gut;Sep2004, Vol. 53 Issue 9, p1385
Academic Journal
Central obesity is a key component of the metabolic syndrome and is associated with increased intra-abdominal fat. It describes the measurement of intra-abdominal fat and abdominal subcutaneous fat areas with computerized tomography. It provides in vivo evidence supporting the hypothesis that a higher rate of free fatty acid (FFA) release from the visceral fat into the portal vein could result in increased hepatic FFA delivery. This would in turn lead to an increase in very low density lipoprotein triglyceride production, insulin resistance and other metabolic complications of obesity. This explains why the waist circumference is the most critical of the indices in predicting the frequency and severity of non-alcoholic fatty liver disease as well as other adverse outcomes of obesity.


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