Is gastric cancer preventable?

Correa, P.
September 2004
Gut;Sep2004, Vol. 53 Issue 9, p1217
Academic Journal
Gastric cancer is a major health burden worldwide and prevention is the most promising strategy to control the disease. The available scientific evidence indicates that curing Helicobacter pylori infection results in a modest retardation of the precancerous process but does not prevent all cancers. Individuals at the highest risk should be cured of their infection and monitored endoscopically to detect dysplasia and "early" cancer, amenable to successful treatment.


Related Articles

  • The benefit of mass eradication of Helicobacter pylori infection: a community-based study of gastric cancer prevention. Yi-Chia Lee; Tony Hsiu-Hsi Chen; Han-Mo Chiu; Chia-Tung Shun; Hung Chiang; Tzeng-Ying Liu; Ming-Shiang Wu; Jaw-Town Lin // Gut;May2013, Vol. 62 Issue 5, p676 

    Objective To evaluate the benefit of mass eradication of Helicobacter pylori infection in reducing premalignant gastric lesions. Design Mass eradication of H pylori infection was started from 2004 for a Taiwanese population with prevalent H pylori infection, who were >30 years of age....

  • H. pylori eradication lowered incidence of secondary gastric cancers.  // Hem/Onc Today;6/25/2008, Vol. 9 Issue 11, p17 

    The article discusses research being done on the link between eradication of Helicobacter pylori after endoscopic resection of gastric cancer and the prevention of the occurrence of secondary gastric cancers. It references a study by Kazutoshi Fukase and colleagues from the department of...

  • Epithelial dysplasia and Helicobacter pylori status in gastric endoscopic biopsies. Gunay, A.; Sen, A. // Gut;Sep2002 Supplement 2, Vol. 51, pA58 

    Objective: Dysplasia of the stomach and Helicobacter pylori (Hp) has been known as precancerous lesions. We aimed to identify gastric dysplasia and Hp status in a series of patients. Methods: Hematoxylin eosin stained paraffin embedded sections from gastric endoscopic biopsies of 297 cases were...

  • Anatomical distribution of H. pylori colonization in the stomach of infected children. Elitsur, Y.; Triest, W.E.; Lawrence, Z. // Gut;Sep2002 Supplement 2, Vol. 51, pA89 

    The anatomical distribution of H. pylori (Hp) colonization in the stomach was previously reported in adults (Genta RM, 1994) but not in children. Aim: To prospectively evaluate the gastric distribution of H. pylori organisms in children who undergo upper endoscopic procedures. Methods: Children...

  • Seventeen-year effects of eradicating Helicobacter pylori on the prevention of gastric cancer in patients with peptic ulcer; a prospective cohort study. Take, Susumu; Mizuno, Motowo; Ishiki, Kuniharu; Hamada, Fumihiro; Yoshida, Tomowo; Yokota, Kenji; Okada, Hiroyuki; Yamamoto, Kazuhide // Journal of Gastroenterology;Jun2015, Vol. 50 Issue 6, p638 

    Background: We previously reported that eradication of Helicobacter pylori in our cohort of patients with peptic ulcer disease reduced their risk of developing gastric cancer to approximately one-third after a mean follow-up period of 3.4 years (up to 8.6 years). We have now followed these...

  • Helicobacter pylori Genotypes in Children from a Population at High Gastric Cancer Risk: No Association with Gastroduodenal Histopathology. Costa Lopes, Ana Isabel; Palha, Ana; Monteiro, Lurdes; Olcastro, Mónica; Pelerito, Ana; Fernandes, Afonso // American Journal of Gastroenterology;Sep2006, Vol. 101 Issue 9, p2113 

    OBJECTIVES: Both bacterial and host determinants underlying differences in histopathology and clinical outcome in H. pylori pediatric infection, as compared to adults, are still poorly documented. Pediatric studies may provide important insights on H. pylori infection immunopathogenesis,...

  • Helicobacter pylori status and associated gastroscopic diagnoses in a tertiary hospital endoscopy population in Rwanda. Walker, Timothy D.; Karemera, Martin; Ngabonziza, Francois; Kyamanywa, Patrick // Transactions of the Royal Society of Tropical Medicine & Hygiene;May2014, Vol. 108 Issue 5, p305 

    Background The study was undertaken to document the prevalence of Helicobacter pylori and endoscopic diagnoses in Rwandans presenting for gastroscopy. Methods We studied an endoscopic database containing 961 consecutive gastroscopy patients at the University Teaching Hospital, Butare, over 12...

  • Helicobacter Pylori and Gastric Precancerous Lesions: An update. Onal, İbrahim Koral; Kurt, Mevlut; Alizadeh, Nasser; Saygili, Fatih; Ibis, Mehmet; Yildiz, Ramazan // Gazi Medical Journal;2015, Vol. 26 Issue 3, p121 

    Gastric cancer (GC) develops through a multistep process known as the gastritis-atrophy-metaplasia-dysplasia-cancer sequence associated with alterations in the expression of host oncogenes and tumor suppressor genes after several decades. Helicobacter pylori (H. pylori) infection is the most...

  • Anti-ulcer drug may prevent stomach cancer.  // Filipino Post;8/13/2015, p9 

    No abstract available.


Read the Article


Sign out of this library

Other Topics