TITLE

Disorders of the blood-aqueous barrier after phacoemulsification in diabetic patients

AUTHOR(S)
Liu, Y.; Luo, L.; He, M.; Liu, X.
PUB. DATE
September 2004
SOURCE
Eye;Sep2004, Vol. 18 Issue 9, p900
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Purpose To evaluate the function of the blood-aqueous barrier after phacoemulsification with implantation of a foldable intraocular lens (IOL) in diabetic patients. Methods All patients were enrolled from those scheduled for phacoemulsification with intraocular lens implantation in Zhonsshan Ophthalmic Center Guanszhou from March 2002 to June 2002. The classification on diabetic retinopathy (DR) was based on the fundus examination after cataract surgery. The blood-aqueous barrier function was examined using the laser flare cell meter (Kowa FC-2000) preoperatively and on postoperative days 1, 7, 30, and 90 by an independent examiner who was masked to the DR classification. Patients were operated by one experienced surgeon as per standard clinical protocol and were provided the same postoperative medical care. A linear regression and Wilcoxon test were used for the analysis. Results A total of 112 patients were divided into three 8roups: patients without diabetic mellitus as normal control (n=56), diabetic patients without diabetic retinopathy (n=2), with nonproliferation diabetic retinopathy (NPDR) (n=37), and diabetic patients with proliferation diabetic retinopathy (PDR) (n=17). All patients were examined and successfully followed up for 3 months after cataract surgery. Aqueous flare mean photon counts in PDR, NPDR, and control eyes were 8.94±0.57, 7.03±0.27, and 6.94±0.34 before surgery and increased to 32.42±0.67, 26.07±0.83, 26.27±1.37 on the first day after surgery (P<0.05), then decreased to 19.86±0.78, 14.08±0.54 and 13.96±1.05 at 7 days after surgery (P<0.05), 13.24±0.29, 9.86±0.33, and 9.07±0.43 at 30 days after surgery (P<0.05); eventually, the counting decreased to 11.25±0.31, 7.24±0.67, and 7.16±0.27 at 90 days after surgery (P<0.05). Linear regression model suggested that other potential variables, such as age, sex, eye (left/right), phaco time, phaco energy, and hypertension were not related to the outcome. For patients without diabetes mellitus and diabetic patients with NPDR, highly statistically significant differences (P<0.05) were found between preoperative flare value and those measured on days 1, 7, and 30 after surgery, but no statistically significant differences (P>0.05) were found between the preoperative flare value and those measured on postoperative days 90. However, patients with PDR still had a higher flare value even on postoperative day 90. The patients with intraoperative iris prolapse had a higher flare value between days 1 and 7 postoperatively. Conclusion Phacoemulsification with a foldable intraocular lens implantation affects the blood-aqueous barrier more severely in diabetic patients with PDR than patients with NPDR and nondiabetic patients.
ACCESSION #
14396977

 

Related Articles

  • IOL scaffolding technique helps prevent nucleus drop. Kumar, Dhivya Ashok; Agarwal, Amar // Ocular Surgery News Europe;May2012, Vol. 23 Issue 5, p25 

    The article discusses the ability of the intraocular lens (IOL) scaffolding technique to prevent nucleus drop without extending the corneal incision. According to the authors, the technique keeps the wound clear corneal. The authors note that the technique is ideal for posterior capsular rupture...

  • Steroid prophylaxis in eyes with uveitis undergoing phacoemulsification. Meacock, W. R.; Spalton, D. J.; Bender, I.; Antcliff, R.; Heatley, C.; Stanford, M. R.; Graham, E. M. // British Journal of Ophthalmology;Sep2004, Vol. 88 Issue 9, p1122 

    Aim: To compare the efficacy of two preoperative steroid regimens for cataract surgery in patients with uveitis. Methods: 40 uveitis patients with cataract Underwent phacoemulsification and intraocular lens (IOL) implantation. Preoperatively they were randomised into two groups: group 1 (20...

  • Phacoemulsification and Foldable Intraocular Lens Implantation in Eyes Filled With Silicone Oil. Öner, Hakan F.; Durak, Ismet; Saatci, Osman A. // Ophthalmic Surgery, Lasers & Imaging;Sep/Oct2003, Vol. 34 Issue 5, p358 

    BACKGROUND AND OBJECTIVE: To evaluate the visual outcome of phacoemulsification and foldable intraocular lens (IOL) implantation in eyes already filled with silicone oil. PATIENTS AND METHODS: Following vitrectomy and silicone oil injection, 16 eyes of 16 consecutive patients undergoing...

  • Comparison of two acrylic intraocular lenses with different haptic designs in patients with combined phacoemulsification and pars plana vitrectomy. Mingels, A.; Koch, J.; Lommatzsch, A.; Pauleikhoff, D.; Heiligenhaus, A. // Eye;Nov2007, Vol. 21 Issue 11, p1379 

    PurposeThe intra- and postoperative characteristics of two foldable single-piece intraocular lenses (IOL) with identical hydrophilic acrylic material, but different haptic designs (Akreos Adapt® and Akreos Fit®), were compared in combined phacoemulsification and pars plana vitrectomy...

  • IOL injector technology aims to keep pace with microincisional phaco platforms. Hasson, Matt // Ocular Surgery News;7/10/2008, Vol. 26 Issue 13, p27 

    The article reports that the discovery of foldable intraocular lenses (IOLs) has pushed phacoemulsification into the mainstream of cataract surgery that allowed for small incisions and minimized complications. It is cited that smaller incisions have become the norm for crystalline lens removal...

  • Anterior capsule cover and axial movement of intraocular lens. Nanavaty, M A; Raj, S M; Vasavada, V A; Vasavada, A R // Eye;Aug2008, Vol. 22 Issue 8, p1015 

    PurposeTo measure optic shift (OS) of a single piece monofocal intraocular lens (IOL) with varying relationships between anterior capsule cover and IOL optic.MethodsThis is a prospective randomized masked study of 150 eyes undergoing phacoemulsification. Eyes received either option: 360o total...

  • Opacification of Two Hydrophilic Acrylic Intraocular Lenses 3 Months After Implantation. Macky, Tamer A.; Werner, Liliana; Soliman, Mahmoud M.; Pandey, Suresh K.; Izak, Andrea M.; Apple, David J. // Ophthalmic Surgery, Lasers & Imaging;May/Jun2003, Vol. 34 Issue 3, p197 

    BACKGROUND AND OBJECTIVE: To report clinical, pathologic, histochemical, ultrastructural, and spectrographic analyses of explanted hydrophilic acrylic intraocular lenses (IOLs) obtained from two patients who had early visual disturbances caused by postoperative opacification of the lens optic....

  • The safely and efficacy of combined phacoemulsification and trabeculectomy with releasable sutures. Stark, W. J.; Goyal, R. K.; Awad, O.; Vito, E.; Kouzis, A. C. // British Journal of Ophthalmology;Feb2006, Vol. 90 Issue 2, p146 

    Aim: To evaluate the combined phacoemulsification with acrylic intraocular lens implantation and trabeculectomy with releasable sutures, without the use of antimetabolites, performed by one surgeon. Methods: A retrospective analysis was performed on 251 eyes of 198 patients after a combined...

  • Reversed vaulted AcrySof intraocular lens presenting as pupillary block. Harsum, S.; Low, S. // Eye;Sep2009, Vol. 23 Issue 9, p1880 

    The article presents a case study of a 68-year-old man with diabetes and end-stage renal failure underwent routine left phacoemulsification. The body of his intraocular lens (IOL) was in the anterior chamber (AC) whereas its haptics were in the capsular bag, causing total pupillary capture. This...

Share

Read the Article

Courtesy of NEW JERSEY STATE LIBRARY

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics