TITLE

Closing the Gap: Electrotonic Junctions in Seizure Control

AUTHOR(S)
Stafstrom, Carl E.
PUB. DATE
September 2004
SOURCE
Epilepsy Currents;Sep/Oct2004, Vol. 4 Issue 5, p174
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Presents a study which examined the involvement of gap junctions in the manifestation and control of the duration of seizures. Information on the function of gap junctions in the brain; Description of the molecular biology of gap junctions; Assessment of gap junctional transmission.
ACCESSION #
14358612

 

Related Articles

  • SIGNAL PROCESSING: Closing the gap. Jones, Rachel // Nature Reviews Neuroscience;Oct2001, Vol. 2 Issue 10, p680 

    Discusses a study which demonstrated that axons of hippocampal neurons are electrically coupled by gap junctions. Information on spikelets; Evidence of axo-axonal gap junctions; Function of axo-axonal coupling.

  • Shaping bursting by electrical coupling and noise. Medvedev, Georgi; Zhuravytska, Svitlana // Biological Cybernetics;Feb2012, Vol. 106 Issue 2, p67 

    Gap-junctional coupling is an important way of communication between neurons and other excitable cells. Strong electrical coupling synchronizes activity across cell ensembles. Surprisingly, in the presence of noise synchronous oscillations generated by an electrically coupled network may differ...

  • Current Literature Gap Junctions in Epileptogenesis: Chicken or Egg? Benardo, Larry S. // Epilepsy Currents;Mar/Apr2004, Vol. 4 Issue 2, p80 

    Comments on the study "Epileptiform Activity in Hippocampal Slice Cultures Exposed Chronically to Bicuculline: Increased Gap-Junctional Function and Expression," by M. Samoilova, J. Li, M. R. Pelletier, K. Wentlandt, Y. Adamchik, C. C. Naus and P. L. Carlen, which examined the influence of...

  • Relevance of gap junctions and large pore channels in traumatic brain injury. Prochnow, Nora // Frontiers in Physiology;Feb2014, Vol. 4/5, p1 

    In case of traumatic brain injury (TBI), occurrence of central nervous tissue damage is frequently aligned with local modulations of neuronal and glial gap junction channel expression levels. The degree of gap junctional protein expression and intercellular coupling efficiency, as well as...

  • nexus.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p1584 

    An encyclopedia entry for "nexus," which refers to a bond between components of a group, is presented.

  • Thalamic Modulation of Cingulate Seizure Activity Via the Regulation of Gap Junctions in Mice Thalamocingulate Slice Chang, Wei-Pang; Wu, José Jiun-Shian; Shyu, Bai-Chuang // PLoS ONE;May2013, Vol. 8 Issue 5, p1 

    The thalamus is an important target for deep brain stimulation in the treatment of seizures. However, whether the modulatory effect of thalamic inputs on cortical seizures occurs through the modulation of gap junctions has not been previously studied. Therefore, we tested the effects of...

  • Analysis of connexin expression during seizures induced by 4-aminopyridine in the rat hippocampus. Laura, Medina-Ceja; Xóchitl, Flores-Ponce; Anne, Santerre; Alberto, Morales-Villagrán // Journal of Biomedical Science;Aug2015, Vol. 22 Issue 1, p1 

    Background: In epilepsy, seizures are generated by abnormal synchronous activity in neurons. In the rat hippocampus (HIP), epileptiform activity has been found to be associated with gap junctions (GJs). GJs are formed by the combination of two hemichannels, each composed of six connexins. At low...

  • Intercellular calcium signalling in cultured renal epithelia: a theoretical study of synchronization mode and pacemaker activity. De Blasio, Birgitte Freiesleben; Iversen, Jens-Gustav; Røttingen, John-Arne // European Biophysics Journal;2004, Vol. 33 Issue 8, p657 

    We investigate a two-dimensional lattice model representation of intercellular Ca2+ signalling in a population of epithelial cells coupled by gap junctions. The model is based on and compared with Ca2+ imaging data from globally bradykinin-stimulated MDCK-I (Madin-Darby canine kidney)-I cell...

  • Expression of connexin genes in the human retina. Söhl, Goran; Joussen, Antonia; Kociok, Norbert; Willecke, Klaus // BMC Ophthalmology;2010, Vol. 10, p27 

    Background: Gap junction channels allow direct metabolically and electrical coupling between adjacent cells in various mammalian tissues. Each channel is composed of 12 protein subunits, termed connexins (Cx). In the mouse retina, Cx43 could be localized mostly between astroglial cells whereas...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics