Guidelines: New Lows for LDL Target Levels

Mitka, Mike
August 2004
JAMA: Journal of the American Medical Association;8/25/2004, Vol. 292 Issue 8, p911
Academic Journal
Reports on an update of key cholesterol level guidelines. How the new guidelines further reduce the safe level of LDL-C or bad cholesterol for all patients; Determination of the National Cholesterol Education Program that patients at risk for heart attacks need to lower their LDL further than previously believed; Definition of patients who are considered high risk and very high risk; Finding of the research that more people probably need to be taking statins as a precaution; How exercise and diet can reduce the number by 30% without medication; Suggestion of acceptable levels for low and moderate risk patients; Ongoing research which may again reduce the acceptable levels of bad cholesterol. INSETS: Old vs New: 001 Adult Treatment Panel III (ATPIII) Guidelines;Key Trial Findings.


Related Articles

  • Serum cholesterol as a risk factor for coronary heart disease revisited. Rossouw, J. E. // South African Journal of Clinical Nutrition;2015, Vol. 28 Issue 1, p34 

    The biology of lipoproteins and lipoprotein particles as mediators of atherosclerosis has been documented extensively. Numerous prospective epidemiological studies have shown a robust relationship between low-density lipoprotein (LDL) cholesterol, or particles bearing apolipoprotein B, and...

  • LDL cholesterol.  // Mayo Clinic Health Letter;May2011, Vol. 29 Issue 5, p1 

    The article discusses new studies on mitigating low-density lipoprotein (LDL) cholesterol levels. It states that statin drugs have been used to break down LDL into smaller particles as a means of mitigating heart disease, as well as atherosclerosis which can also impact the brain. New studies...

  • A 39-Year-Old Woman With Hypercholesterolemia. Mittleman, Murray A. // JAMA: Journal of the American Medical Association;7/19/2006, Vol. 296 Issue 3, p319 

    This article focuses on a conference between patient and doctor concerning the case of a 39-year-old African-American woman with hypercholesterolemia, well-controlled hypertension and a maternal history of breast cancer. Although her 10-year risk of coronary heart disease (CHD) is relatively low...

  • Taking statins.  // Mayo Clinic Health Letter;Nov2015, Vol. 33 Issue 11, p4 

    The article discusses joint guidelines from the American College of Cargiology and American Heart Association that can help streamline the assessment of who can benefit from taking a statin with respect to overall risk of heart attack and stroke. The guidelines suggest specific regimens of...

  • Benefits of long-term statin treatment.  // Australian Journal of Pharmacy;May2012, Vol. 93 Issue 1104, p92 

    The article reports on a study to examine the long-term effects of statin in lowering low-density lipoprotein (LDL) cholesterol. A follow-up randomized trial was carried out on patients who are at high risk of vascular and non-vascular outcomes. The results concluded large reduction in chances...

  • Education: Viewpoint - Statins in ischaemic stroke. Sever, Peter; Poulter, Neil // GP: General Practitioner;5/12/2014, p12 

    The article argues on the role of statins in ischaemic stroke prevention. Topics discussed include guidelines from Europe and the U.S. on statins as secondary treatment which targets low-density lipoprotein (LDL) cholesterol, the implications of these guidelines to statin therapy in Great...

  • PCSK9 Inhibitors: Are We on the Verge of a Breakthrough? Yang, E. // Clinical Pharmacology & Therapeutics;Dec2015, Vol. 98 Issue 6, p590 

    Statins are first-line therapy for lowering cholesterol and reducing cardiovascular events. A significant need for new lipid-modifying therapies remains for patients unable to tolerate statins or achieve guideline-based cholesterol targets. Proprotein convertase subtilisin/kexin type 9 (PCSK9)...

  • Are treatment targets for hypercholesterolemia evidence based? Systematic review and meta-analysis of randomised controlled trials. Y Lebenthal // Archives of Disease in Childhood;Sep2010, Vol. 95 Issue 9, p673 

    OBJECTIVE: Search for evidence supporting target age, level of intervention and target values for low-density lipoprotein (LDL) cholesterol levels in children with familial hypercholesterolemia. DESIGN: Systematic review and meta-analysis. PubMed, Medline, CINAHL and Cochrane Reviews databases...

  • Cut Your Heart Attack Risk in Half. Quinn, Joan // Prevention;Nov2001, Vol. 53 Issue 11, p48 

    Focuses on ways to predict and reduce heart attack risk from high cholesterol. INSET: The Risk Factors.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics