Acquired Long QT Syndrome and Monomorphic Ventricular Tachycardia After Alternative Treatment With Cesium Chloride for Brain Cancer

Dalal, Anuj K.; Harding, John D.; Verdino, Ralph J.
August 2004
Mayo Clinic Proceedings;Aug2004, Vol. 79 Issue 8, p1065
Academic Journal
Individuals searching for symptomatic relief or a potential cure are Increasingly seeking and using nontraditional therapies for their various diseases. Little is known about the potential adverse effects that patients may encounter while undergoing these alternative treatments. Cesium chloride is an unregulated agent that has been reported to have antineoplastic properties. Cesium chloride is advertised as an alternative agent for many different types of cancers and can be purchased easily on the internet. Recently, QT prolongation and polymorphic ventricular tachycardia were reported in several patients taking cesium chloride as alternative treatment for cancer. We report acquired QT prolongation and sustained monomorphic ventricular tachycardia in a patient who self-initiated and completed a course of cesium chloride as adjunctive treatment for brain cancer.


Related Articles

  • Mechanism of U wave and polymorphic ventricular tachycardia in a canine tissue model of Andersen�Tawil syndrome. Morita, Hiroshi; Zipes, Douglas P.; Morita, Shiho T.; Wu, Jiashin // Cardiovascular Research;Aug2007, Vol. 75 Issue 3, p510 

    Abstract: Objective: Andersen�Tawil syndrome (ATS) is a channelopathy affecting inward rectifier potassium I K1 with QT prolongation, large U waves, and frequent ventricular tachycardia (VT). Although ATS is clinically defined and genetically identified, its electrophysiological mechanism...

  • Inhibition of Sodium Current by Taurine Magnesium Coordination Compound Prevents Cesium Chloride-Induced Arrhythmias. Yin, Yongqiang; Wen, Ke; Wu, Yanna; Kang, Yi; Lou, Jianshi // Biological Trace Element Research;May2012, Vol. 146 Issue 2, p192 

    The mechanism(s) by which taurine magnesium coordination compound (TMCC) inhibits experimental arrhythmias remains poorly understood. The purpose of this study was to observe the effects of TMCC against cesium chloride-induced arrhythmia in the rabbit heart and find whether the antiarrhythmic...

  • Stop cancer, shoot the messenger. Coghlan, Andy // New Scientist;9/30/95, Vol. 147 Issue 1997, p24 

    Reports on the use of the drug called SU101, a drug blocking the chemical signals that tell cancer cells to grow and divide, to patients with advanced brain cancers. Drug's targeting of the signal transduction activated by a platelet-derived growth factor.

  • Q&A SUPRAVENTRICULAR ARRHYTHMIAS. Slater, William; Korona, Doris // Cortlandt Forum;10/25/2000, Vol. 13 Issue 10, p125 

    Answers questions about supraventricular arrhythmia. Diagnosis; Two mechanisms of occurrence; Treatment of sinus node tachycardia; Intra-atrial tachycardias; Digitalis toxicity; Management of intra-atrial tachycardias; Prevention; A-V nodal tachycardias.

  • Cesium chloride induced ventricular arrhythmias in dogs: three-dimensional activation patterns and their relation to the cesium dose applied. Senges, Julia C.; Sterns, Laurence D.; Freigang, Kirsten D.; Bauer, Alexander; Becker, Rüdiger; Kübler, Wolfgang; Schoels, Wolfgang // Basic Research in Cardiology;Mar2000, Vol. 95 Issue 2, p152 

    Introduction: Cesium chloride has widely been used in experimental models to produce various ventricular arrhythmias. The study was designed to evaluate whether type and mechanism of these arrhythmias are dose-dependent. Methods: In 7 dogs with acute AV-block, 60 pins containing 4 bipolar...

  • CYTOPIA BEGINS SECOND PHASE II STUDY IN BRAIN CANCER.  // Worldwide Biotech;Oct2008, Vol. 20 Issue 10, p8 

    The article reports on the commencement of enrolment for Melbourne, Victoria-based Cytopia Limited's Phase Ib/II study of CYT997, the company's novel vascular-disrupting antineoplastic agent. The drug is aimed at patients with an aggressive form of brain cancer known as glioblastoma multiforme...

  • Synthesis and Evaluation of Some 16-Benzylidene Substituted 3,17- Dioximino Androstene Derivatives as Anticancer Agents. Dubey, Sonal; Piplani, Poonam; Jindal, Dharam P. // Letters in Drug Design & Discovery;Nov2005, Vol. 2 Issue 7, p537 

    The synthesis of some steroidal dioximes (22-29) and their in vitro antineoplastic activity are described in this report. The oximino functionality was incorporated at position 3 and 17 of the 16- benzylidene substituted steroidal nucleus to study the importance of dioximino moiety on anticancer...

  • Carboplatin/etoposide/thiotepa.  // Reactions Weekly;4/8/2006, Issue 1096, p7 

    Presents a case of encephalopathy in a patient after receiving antineoplastic therapy for recurrent brain cancer. Dosage of carboplatin received by the patient; Symptoms experienced after treatment with antiviral and antibacterial agents and parenteral nutrition; Results of...

  • Cationized Albumin Conjugated Solid Lipid Nanoparticles as Vectors for Brain Delivery of an Anti-Cancer Drug. Agarwal, Abhinav; Majumder, Saikat; Agrawal, Himanshu; Majumdar, Subrata; Agrawal, Govind P. // Current Nanoscience;Feb2011, Vol. 7 Issue 1, p71 

    The present study investigates the prospective of surface engineered solid lipid nanoparticles as vectors to bypass BBB and provide improved therapeutic efficacy of encapsulated anti-cancer drug Methotrexate (MTX). MTX loaded SLNs were prepared and conjugated with cationic bovine serum albumin...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics