LUNG ALERT: The "hygiene hypothesis" revisited

Hurst, J. R.
August 2004
Thorax;Aug2004, Vol. 59 Issue 8, p698
Academic Journal
The "hygiene hypothesis" suggests that decreasing exposure to micro-organisms during infancy is responsible for the increasing prevalence of atopy. However, while a decreased risk of atopic disease is associated with various surrogate markers of microbial exposure including early attendance at day care, a greater number of siblings and living on a farm, specific associations between clinical episodes of infection and atopy remain ill defined and the possible mechanisms obscure. Two recent research papers have sought to characterize further the links between infection and atopy.


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