Gastrointestinal manifestations of postnatal cytomegalovirus infection in infants admitted to a neonatal intensive care unit over a five year period

Cheong, J L Y; Cowan, F M; Modi, N
July 2004
Archives of Disease in Childhood -- Fetal & Neonatal Edition;Jul2004, Vol. 89 Issue 4, pf367
Academic Journal
Sixteen cases of postnatal cytomegalovirus (CMV) infection were identified in a neonatal intensive care unit population over a five year period. Eleven of these infants had gastrointestinal signs of the time of presentation. These ranged from minor and transmit (abdominal distension and eternal lead intolerance) to saver and life threatening (protein losing enteropathy , diarrhea, and hypermatroemic dehydration). An initial diagnosis of necrotising enterocolitis was common, but no infant showed intestinal or hepatic portal pneumatosis. The gestational are of the infants was 24-38 weeks. All had received fresh maternal breast milk. It is suggested that CMV enterits is added to the specturm of clinical manifestations of postnatal CMV infaction. Signs suggestive of necrotising entercolitis with atypical features should prompt investigations for CMV infection.


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