Interictal Burden of Cluster Headache: Results of the EUROLIGHT Cluster Headache Project, an Internet‐Based, Cross‐Sectional Study of People With Cluster Headache

Pohl, Heiko; Gantenbein, Andreas R.; Sandor, Peter S.; Schoenen, Jean; Andrée, Colette
February 2020
Headache: The Journal of Head & Face Pain;Feb2020, Vol. 60 Issue 2, p360
Academic Journal
Objective: The aim of this study was to measure the interictal burden (IIB) associated with cluster headache (CH). Background: CH is characterized by an alternation of excruciatingly painful attacks and pain‐free periods. Absence of pain does not necessarily imply absence of symptoms, though. Some may persist or improve more slowly than pain; others may arise in between attacks. Methods: Participants filled out an online survey based on the EUROLIGHT questionnaire. Inclusion criteria were a reported diagnosis of CH and residency in a European country; exclusion criteria were refusal to give informed consent and to complete the questionnaire. Results: Most of the burden was related to higher headache frequencies: ongoing symptoms despite pain freedom, impaired autonomy due to avoidance of triggers, reluctance to tell others about the disease, and the feeling of not being understood by family and friends, employers and colleagues. Irreversible, potentially accumulating burden may occur if headache frequency is high; examples are impairment of career options, relationships, and family planning issues. Worrying about future attacks and avoiding potential triggers occur independently from attack frequency and disease duration. There were no differences between the in‐bout and the out‐bout period among participants with episodic CH. Participants with chronic CH reported greater IIB. Conclusions: Even between attacks CH can have a huge and potentially irreversible impact on life. Different types of IIB were identified, all of which may contribute to the total burden of disease. As cumulative burden might be irreversible, prevention strategies need to be developed.


Related Articles

  • Fatigue Among Short- and Long-Term Thyroid Cancer Survivors: Results from the Population-Based PROFILES Registry. Husson, Olga; Nieuwlaat, Willy-Anne; Oranje, Wilma A.; Haak, Harm R.; van de Poll-Franse, Lonneke V.; Mols, Floortje // Thyroid;Oct2013, Vol. 23 Issue 10, p1247 

    Background: The aims of this study were (i) to obtain insight into the prevalence of fatigue among short- and long-term thyroid cancer (TC) survivors, by comparing a sample of TC survivors with an age- and sex-matched normative population, and (ii) to investigate which demographic, clinical, and...

  • A descriptive analysis of the relationship between quality of life and distress in individuals with head and neck cancer. Bornbaum, Catherine; Fung, Kevin; Franklin, Jason; Nichols, Anthony; Yoo, John; Doyle, Philip // Supportive Care in Cancer;Sep2012, Vol. 20 Issue 9, p2157 

    Purpose: Both short- and long-term outcomes for individuals with head and neck cancer (HNCa) may be influenced by multiple factors. Identification of distress in those with HNCa may provide a critical dimension that influences quality of life (QoL). Consequently, this investigation assessed...

  • Is Test Anxiety a Problem Among Medical Students: A Cross Sectional Study on Outcome of Test Anxiety among Medical Students? Saravanan, Coumaravelou; Kingston, Rajiah; Gin, May // International Journal of Psychological Studies;Sep2014, Vol. 6 Issue 3, p24 

    Pathological anxiety towards an exam intensifies psychological distress and reduces academic motivation. The present study aimed to identify the prevalence of test anxiety and psychological distress. Additionally, the present study examined the extent to which test anxiety predicts psychological...

  • Severity of depression and anxiety in obstructive sleep apnea syndrome. Asghari, Alimohamad; Mohammadi, Fatemeh; Kamrava, Seyed; Tavakoli, Saman; Farhadi, Mohammad // European Archives of Oto-Rhino-Laryngology;Dec2012, Vol. 269 Issue 12, p2549 

    Obstructive sleep apnea (OSA) is a common sleep disorder which can result in mood problems. The aim of this study was to evaluate the severity of depression and anxiety symptoms as the most prevalent psychological disturbances present in different severity of OSA. We performed a cross-sectional...

  • Individual differences in physical symptom burden and psychological responses in individuals with chronic lymphocytic leukemia. Morrison, Eleshia; Flynn, Joseph; Jones, Jeffrey; Byrd, John; Andersen, Barbara; Morrison, Eleshia J; Flynn, Joseph M; Byrd, John C; Andersen, Barbara L // Annals of Hematology;Dec2016, Vol. 95 Issue 12, p1989 

    Chronic lymphocytic leukemia (CLL) is an incurable illness, with some patients requiring no treatment until disease progression. Burden from physical symptoms has been associated with depression, anxiety, and stress in cancer patients. Additionally, patient factors, i.e., individual differences,...

  • Síntomas de ansiedad y depresión en adolescentes escolarizados de 10 a 17 años en Chía, Colombia. Ospina-Ospina, Fanny del Carmen; Hinestrosa-Upegui, María F.; Paredes, María C.; Guzmán, Yahira; Granados, Carlos // Revista de Salud Pública;dec2011, Vol. 13 Issue 6, p908 

    Objective This study was aimed at estimating the prevalence of symptoms of depression and anxiety amongst 10 to 17 year-old adolescents still attending school using the CDI and SCARED questionnaires for early screening in Chía, a town near Bogota, from 2008 to 2010. Method This was a...

  • Measuring population mental health and social well-being. Lente, Eric; Barry, Margaret; Molcho, Michal; Morgan, Karen; Watson, Dorothy; Harrington, Janas; McGee, Hannah // International Journal of Public Health;Apr2012, Vol. 57 Issue 2, p421 

    Objectives: This paper examines the relationships between indicators of positive and negative dimensions of mental health, social well-being and physical health. Methods: The paper reports on data collected in the third National Survey of Lifestyle, Attitudes and Nutrition (SLÁN 2007), a...

  • The importance of both workplace and private life factors in psychological distress: a large cross-sectional survey of French railway company employees. Evans, David; Mallet, Luc; Flahault, Antoine; Cothereau, Catherine; Velazquez, Sébastien; Capron, Loïc; Lejoyeux, Michel // Social Psychiatry & Psychiatric Epidemiology;Aug2013, Vol. 48 Issue 8, p1211 

    Purpose: The psychological well-being of employees is a priority in occupational health. This study aimed to estimate the prevalence of psychological distress among employees of a large French company, to calculate the associations between distress and stressors in the workplace and private life...

  • Management of Patient-Reported Outcome (PRO) Alerts in Clinical Trials: A Cross Sectional Survey. Kyte, Derek; Ives, Jonathan; Draper, Heather; Calvert, Melanie // PLoS ONE;1/19/2016, Vol. 11 Issue 1, p1 

    Background: Assessment of patient-reported outcomes (PROs) provides valuable information to inform patient-centered care, but may also reveal ‘PRO alerts’: psychological distress or physical symptoms that may require an immediate response. Ad-hoc management of PRO alerts in...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics