TITLE

K103N Mutation in Antiretroviral Therapy-Naive African Patients Infected with HIV Type 1

AUTHOR(S)
Akinsete, Omobosola; Hirigoyen, Diane; Cartwright, Charles; Schut, Ron; Kantor, Rami; Henry, Keith
PUB. DATE
August 2004
SOURCE
Clinical Infectious Diseases;8/15/2004, Vol. 39 Issue 4, p575
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Most of the information about genetic sequencing and drug susceptibility of human immunodeficiency virus type 1 (HIV-1) is derived from the study of HIV-1 subtype B. Worldwide, most people infected with HIV-1 are infected with non-subtype B viruses and live in developing countries We report 3 cases of antiretroviral-naive African immigrants infected with HIV-1 strains possessing the K103N mutation in the reverse transcriptase gene, which confers high-level resistance to all nonnucleoside reverse transcriptase inhibitors.
ACCESSION #
14048119

 

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