TITLE

Determinants of overdose incidents among illicit opioid users in 5 Canadian cities

AUTHOR(S)
Fischer, Benedikt; Brissette, Suzanne; Brochu, Serge; Bruneau, Julie; El-Guebaly, Nady; Noël, Lina; Rehm, Jürgen; Tyndall, Mark; Wild, Cameron; Mun, Phil; Haydon, Emma; Baliunas, Dolly
PUB. DATE
August 2004
SOURCE
CMAJ: Canadian Medical Association Journal;8/3/2004, Vol. 171 Issue 3, p235
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: Drug overdose is a major cause of death and illness among illicit drug users. Previous research has indicated that most illicit drug users experience nonfatal overdoses and has suggested a variety of factors that are associated with risk of overdose. In this study, we examined the occurrence of and the factors associated with nonfatal overdoses within a Cana-dian sample of illicit opioid users not enrolled in treatment at the time of study recruitment. Methods: Interviewers used a standard questionnaire to collect data on sociodemographic characteristics, drug use, health and health care, experience in the criminal justice system and treatment for drug problems; they also performed standard as-sessments for mental health and infectious disease. The associ-ation between overdose and sociodemographic and drug-use factors was examined with X2 and t test analyses; marginally significant variables were examined with logistic regression to determine independent effects. Results: A total of 679 subjects were interviewed; 651 provided answers sufficient for this analysis. One hundred and twelve (17.2%) of the 651 respondents reported an overdose episode in the previous 6 months. In the logistic regression analysis (af-ter adjustment for sociodemographic factors), homelessness, noninjection use of hydromorphone in the past 30 days and involvement in drug treatment in the past 12 months were pre-dictors of overdose ( p< 0.05). Interpretation: Overdose poses a considerable health risk for illicit opioid users. We found that a diverse set of factors was associ-ated with overdose episodes. Prevention efforts will likely be more effective if they can be directed to specific causal factors.
ACCESSION #
13924792

 

Related Articles

  • Correction.  // Minnesota Medicine;May2013, Vol. 96 Issue 5, p5 

    A correction to the article "The Opioid Crisis" that was published in the March 2013 issue is presented.

  • Opioid Overdose: When Good Drugs Break Bad. Berge, Keith H.; Burkle, Christopher M. // Mayo Clinic Proceedings;Apr2014, Vol. 89 Issue 4, p437 

    An introduction is presented in which the editor discusses various reports within the issue on topics including overdose (OD) of opioid, drug abuse and laws defining the use of opioid in the U.S.

  • The Contribution of Patient Satisfaction to the Opiate Abuse Epidemic. Hirsch, Ronald Lauren // Mayo Clinic Proceedings;Aug2014, Vol. 89 Issue 8, p1168 

    A letter to the editor is presented in response to the article "Opioid Overdose: When Good Drugs Break Bad," by K. H. Berge et al. in the 2014 issue.

  • In reply--The Contribution of Patient Satisfaction to the Opiate Abuse Epidemic. Berge, Keith H.; Burkle, Christopher M. // Mayo Clinic Proceedings;Aug2014, Vol. 89 Issue 8, p1168 

    A response from the article "Opioid Overdose: When Good Drugs Break Bad," in the 2014 issue is presented.

  • Erratum.  // MMWR: Morbidity & Mortality Weekly Report;1/13/2017, Vol. 66 Issue 1, p35 

    Corrections to the article "Increases in Drug and Opioid-Involved Overdose Deaths: United States, 2010-2015" in Vol. 65, Nos. 50 & 51 are presented.

  • Acute opioid dependence: characterizing the early adaptations underlying drug withdrawal. Harris, Andrew C.; Gewirtz, Jonathan C. // Psychopharmacology;Apr2005, Vol. 178 Issue 4, p353 

    Rationale: While opioid withdrawal is typically studied under conditions of chronic (i.e., continuous) drug administration, withdrawal signs can also be demonstrated in both humans and animals after a single opioid exposure. This phenomenon, termed acute dependence, may be useful in...

  • Cognitive function during early abstinence from opioid dependence: a comparison to age, gender, and verbal intelligence matched controls. Rapeli, Pekka; Kivisaari, Reetta; Autti, Taina; Kähkönen, Seppo; Puuskari, Varpu; Jokela, Olga; Kalska, Hely // BMC Psychiatry;2006, Vol. 6, p9 

    Background: Individuals with opioid dependence have cognitive deficits during abuse period in attention, working memory, episodic memory, and executive function. After protracted abstinence consistent cognitive deficit has been found only in executive function. However, few studies have explored...

  • Preventing opioid overdoses in Europe: a critical assessment of known risk factors and preventative measures. Giraudon, Isabelle; Vicente, Julián // Drugnet Europe;Oct-Dec2012, Issue 80, p7 

    The article offers information on a study linking risk factors to opioid overdoses and the measures to be considered to lessen fatal outcomes.

  • Management of opioid addiction with buprenorphine: French history and current management. Poloméni, Pierre; Schwan, Raymund // International Journal of General Medicine;2014, Vol. 7, p143 

    The way in which opioid addiction is managed in France is unique, as it is based on the prescription of buprenorphine by general practitioners and is dispensed by retail pharmacies. This policy has had a direct, positive impact on the number of deaths caused by heroin overdose, which was reduced...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics