TITLE

Acute Pain in Herpes Zoster and Its Impact on Health-Related Quality of Life

AUTHOR(S)
Katz, Jennifer; Cooper, Edith M.; Walther, Robert R.; Sweeney, Eugene W.; Dworkin, Robert H.
PUB. DATE
August 2004
SOURCE
Clinical Infectious Diseases;8/1/2004, Vol. 39 Issue 3, p342
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Although the effects of postherpetic neuralgia on physical and emotional functioning have been examined in a number of studies, the impact of acute pain in herpes zoster ("shingles") on health-related quality of life has been neglected. We describe the characteristics of herpes zoster pain and examine its relationship to physical, role, social, and emotional functioning in 110 patients with herpes zoster. When we controlled for relevant covariates, we found that greater pain burden, as assessed by the product of pain intensity and duration, was associated with poorer physical functioning, increased emotional distress, and decreased role and social functioning. The results demonstrate that herpes zoster pain has broad effects on the daily lives of patients and on their emotional health. The increasing incidence of herpes zoster that can be anticipated as the population ages requires that clinical trials that examine interventions to prevent or treat herpes zoster pain be given a high priority.
ACCESSION #
13920011

 

Related Articles

  • A cross-sectional survey of health state impairment and treatment patterns in patients with postherpetic neuralgia. Van Seventer, Robert; Sadosky, Alesia; Lucero, Melanie; Dukes, Ellen // Age & Ageing;Mar2006, Vol. 35 Issue 2, p132 

    Background: postherpetic neuralgia (PHN) develops in 8-24% of patients with herpes zoster. Few studies have evaluated the patient burden and treatment of PHN in general practice. Objectives: to determine the patient burden of PHN with respect to pain intensity and impact on patient functioning...

  • What is the prognosis of postherpetic neuralgia? Gazewood, John D.; Meadows, Susan // Journal of Family Practice;Jun2003, Vol. 52 Issue 6, p496 

    The article explains the prognosis of postherpetic neuralgia. This condition is defined as pain that persists more than one month following onset herpes zoster. It occurs rarely among patients aged less than 50 years with herpes zoster. Although the incidence, duration, and severity of...

  • Botulinum Toxin Reduction Pain in Postherpetic Neuralgia. Emad, Mohamad Reza; Emad, Maryam; Taheri, Parisa // Journal of Isfahan Medical School;1/10/2011, Vol. 28 Issue 114, p1 

    Background: The most common complication of herpes zoster is postherpetic neuralgia (PHN), which can cause chronic and debilitating pain. In some patients, pain persists for weeks or even years after regression of the rash and many drugs and methods should be used to treat the pain. As many...

  • Survey on the Treatment of Postherpetic Neuralgia in Korea; Multicenter Study of 1,414 Patients. Nahm, Francis Sahngun; Sang Hun Kim; Hong Soon Kim; Jin Woo Shin; Sie Hyeon Yoo; Myung Ha Yoon; Doo Ik Lee; Youn Woo Lee; Jun Hak Lee; Young Hoon Jeon; Dae Hyun Jo // Korean Journal of Pain;Jan2013, Vol. 26 Issue 1, p21 

    Background: Postherpetic neuralgia (PHN) is a serious complication resulting from herpes zoster infections, and it can impair the quality of life. In order to relieve pain from PHN, various treatments, including pharmacological and interventional methods have been used. However, little...

  • Prevalence of postherpetic neuralgia after a first episode of herpes zoster: prospective study with long term follow up. Cunningham; Helgason, Sigurdur; Petursson, Gunnar; Gudmundsson, Sigurdur; Sigurdsson, Johann A // BMJ: British Medical Journal (International Edition);09/30/2000, Vol. 321 Issue 7264, p794 

    Objective: To estimate the frequency, duration, and clinical importance of postherpetic neuralgia after a single episode of herpes zoster.Design: Prospective cohort study with long term follow up.Setting: Primary health care in Iceland.Participants: 421 patients with a single episode of herpes...

  • Herpes Zoster and Postherpetic Neuralgia: Diagnosis and Therapeutic Considerations. Roxas, Mario // Alternative Medicine Review;Jun2006, Vol. 11 Issue 2, p102 

    Herpes zoster (HZ), also known as shingles, is a painful vesicular rash resulting from reactivation of the virus that also causes chickenpox - Varicella zoster virus (VZV). Typically, the rash runs its course in a matter of 4-5 weeks. The pain, however, may persist months, even years, after the...

  • Effect of duration of postherpetic neuralgia on efficacy analyses in a multicenter, randomized, controlled study of NGX-4010, an 8% capsaicin patch evaluated for the treatment of postherpetic neuralgia. Webster, Lynn R.; Tark, Marvin; Rauck, Richard; Tobias, Jeffrey K.; Vanhove, Geertrui F. // BMC Neurology;2010, Vol. 10, p92 

    Background: Postherpetic neuralgia (PHN) is a painful and difficult to treat complication of acute herpes zoster. Current treatment options provide only partial relief and are often limited by poor tolerability. We evaluated the safety and efficacy of a single 60-minute application of NGX-4010,...

  • A Vaccine to Prevent Herpes Zoster and Postherpetic Neuralgia in Older Adults. Oxman, M.N.; Levin, M.J.; Johnson, G.R.; Schmader, K.E.; Straus, S.E.; Gelb, L.D.; Arbeit, R.D.; Simberkoff, M.S.; Gershon, A.A.; Davis, L.E.; Weinberg, A.; Boardman, K.D.; Williams, H.M.; Zhang, J. Hongyuan; Peduzzi, P.N.; Beisel, C.E.; Morrison, V.A.; Guatelli, J.C.; Brooks, P.A.; Kauffman, C.A. // New England Journal of Medicine;6/2/2005, Vol. 352 Issue 22, p2271 

    Background: The incidence and severity of herpes zoster and postherpetic neuralgia increase with age in association with a progressive decline in cell-mediated immunity to varicella–zoster virus (VZV). We tested the hypothesis that vaccination against VZV would decrease the incidence,...

  • A Review Of Postherpetic Neuralgia. Flossos, Andrew; Kostakou, Chrysoula // Internet Journal of Pain, Symptom Control & Palliative Care;2006, Vol. 4 Issue 2, p3 

    Postherpetic neuralgia is one of the most feared complications of herpes zoster and one of the most painful conditions seen in pain practice. Both conditions occur much more commonly in elderly patients and immunosuppressed individuals, and stress may be an important instigator of both...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics