TITLE

Homocysteine-lowering therapy did not prevent stroke recurrence

AUTHOR(S)
Hankey, Graeme J.
PUB. DATE
July 2004
SOURCE
ACP Journal Club;Jul/Aug2004, Vol. 141 Issue 1, p21
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents the information that homocysteine lowering therapy did not prevent stroke recurrence. In patients with nondisabling cerebral infarction, a multivitamin tablet with high doses of pyridoxine, cobalamin, and folic acid did not differ from a low-dose tablet for reducing recurrent stroke. 3680 patients who were ≥ 35 years of age and had nondisabling ischemic stroke and elevated total homocysteine levels. Exclusion criteria included embolic stroke, other major neurologic illness, life expectancy < 2 years, need for dialysis, and untreated anemia or vitamin B12 deficiency.
ACCESSION #
13916266

 

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