TITLE

Levofloxacin-based triple regimens were better than standard quadruple regimens for second-line eradication of Helicobacter pylori

AUTHOR(S)
Chan, Francis K.L.
PUB. DATE
July 2004
SOURCE
ACP Journal Club;Jul/Aug2004, Vol. 141 Issue 1, p19
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Levofloxacin-based triple regimens were better than standard quadruple regimens for second-line eradication of Helicobacter pylori. Patients who received LAR or LTR regimens had higher rates of H. pylori eradiation than did those who received the 7TMBR or 14TMBR regimens. In patients with Helicobacter pylori infection in whom triple therapy had previously failed, 10-day levofloxacin-based triple regimens were more effective and had fewer side effects than standard 10- or 14-day quadruple regimens. Currently, the recommended second-line treatment for H. pylori infection is quadruple therapy consisting of a proton-pump inhibitor, bismuth salt, metronidazole, and tetracycline for a minimum of 7 days.
ACCESSION #
13916264

 

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