Pravastatin reduced major CHD events in patients with abnormal fasting glucose and a history of CHD

Gami, Apoor S.
July 2004
ACP Journal Club;Jul/Aug2004, Vol. 141 Issue 1, p5
Academic Journal
The article presents an overview of secondary prevention of cardiovascular events with long-term pravastatin in patients with diabetes or impaired fasting glucose: results from the LIPID trial. In patients with abnormal fasting glucose (diabetes and impaired fasting glucose) and a history of myocardial infarction or unstable angina, pravastatin reduced major coronary heart disease events. HMG CoA-reductase inhibitors (statins) decrease CV morbidity and mortality in patients with CHD. This substudy by Professor A. Keech, and colleagues of the LIPID trial adds to the evidence that this remains true for patients who also have diabetes or IFG. The magnitude of treatment effect was consistent with that of diabetes subgroups in other secondary prevention statin trials.


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