Serotonin and vasoactive intestinal peptide antagonists attenuate rotavirus diarrhoea
- Comparison of NSP4 protein between group A and B human rotaviruses: detection of novel diarrhea-causing sequences in group B NSP4. Ishino, M.; Mise, K.; Takemura, H.; Ahmed, M. U.; Alam, M. M.; Naik, T. N.; Kobayashi, N. // Archives of Virology;Jan2006, Vol. 151 Issue 1, p173
The human group B rotavirus is a causative agent of severe adult diarrhea. In this study, we analyzed the NSP4 structure of a group B rotavirus strain, CAL-1, and determined whether enterotoxin activity was present in CAL-1 NSP4. CAL-1 NSP4 was comprised of 219 amino acids which was longer than...
- Prevalence of Rotavirus-induced Diarrhoea among Children under 5 Years in Ilorin, Nigeria. M. S. Odimayo; W. I. Olanrewaju; S. A. Omilabu; Boaz Adegboro // Journal of Tropical Pediatrics;Oct2008, Vol. 54 Issue 5, p343
Diarrhoea disease is an important cause of morbidity and mortality in Nigerian children and rotavirus has been identified as an important causative agent among children below 5 years. We determined the prevalence of rotavirus-induced diarrhoea among under-5 s by electropherotyping. Stool samples...
- tachykinin. // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p2270
A definition of the medical term "tachykinin," which refers to a large family of peptides that act as neurotransmitters in the nervous system, is presented.
- Hemokinins and endokinins. N. M. Page // Cellular & Molecular Life Sciences;Jun2004, Vol. 61 Issue 13, p1652
The mammalian tachykinins are a family of peptides that, until recently, has included substance P (SP), neurokinin A and neurokinin B. Since, the discovery of a third preprotachykinin gene ( TAC4), the number of tachykinins has more than doubled to reveal several species-divergent peptides. This...
- Characterization of Rotavirus Strains Detected in Windhoek, Namibia during 1998-1999. Page, Nicola; Pager, Cara; Steele, A. Duncan // Journal of Infectious Diseases;9/1/2010 Supplement, Vol. 202, pS162
Background. Namibia, located on the southwestern coast of southern Africa, is characterized by vast deserts, limited fresh water, and low population density. Mortality estimates among children <5 of age are 63 deaths per 1000 live-births, with diarrheal diseases contributing to 3% of these...
- Amide Mono Thioxylated Derivatives of MEN 10627. Altamura, M.; Balacco, G.; Giolitti, A.; Guidi, A.; Patacchini, R.; Renzetti, A. R.; Triolo, A.; Maggi, C. A. // Letters in Drug Design & Discovery;Jul2004, Vol. 1 Issue 3, p285
The thioxylation of the potent Neurokinin A antagonist MEN 10627 by Lawesson's reagent showed to be potentially useful for the post-synthetic manipulation of the related family of structurally peculiar bicyclic hexapeptides, whose synthesis in combinatorial manner has been recently described.
- rotavirus. // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p2052
A definition of the term "rotavirus" which refers to any of a group of double-stranded ribonucleic acid (RNA) viruses causing diarrhea in children is presented.
- The Dominican Republic Introduces Rotavirus Vaccine into National Immunization Schedule. // Immunization Newsletter;Aug2012, Vol. 34 Issue 4, p4
The article reports on the introduction of rotavirus vaccine by the Dominican Republic on July 4, 2012 into its national immunization schedule for preventing diarrhea in children and avoid mortality.
- Genetic analysis of an ADRV-N-like novel rotavirus strain B219 detected in a sporadic case of adult diarrhea in Bangladesh. Alam, M. M.; Kobayashi, N.; Ishino, M.; Ahmed, M. S.; Ahmed, M. U.; Paul, S. K.; Muzumdar, B. K.; Hussain, Z.; Wang, Y.-H.; Naik, T. N. // Archives of Virology;Jan2007, Vol. 152 Issue 1, p199
An unusual human rotavirus strain B219 was detected in a stool specimen from a 65-year old patient with diarrhea in Bangladesh during April 2002. Cloning and sequence analysis of five genes of the B219 strain indicated that this virus is genetically closely related to the ADRV-N strain, which...